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S6387

Sigma-Aldrich

Sulfadiazine sodium salt

≥98% (HPLC)

Synonym(s):

4-Amino-N-(2-pyrimidinyl)benzenesulfonamide sodium salt, SPS Agar Supplement

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About This Item

Empirical Formula (Hill Notation):
C10H9N4NaO2S
CAS Number:
Molecular Weight:
272.26
Beilstein:
4068213
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥98% (HPLC)

form

crystalline powder

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

SMILES string

Nc1ccc(cc1)S(=O)(=O)N([Na])c2ncccn2

InChI

1S/C10H9N4O2S.Na/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1

InChI key

JLDCNMJPBBKAHH-UHFFFAOYSA-N

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General description

Sulfadiazine sodium salt is a broad-spectrum antibiotic belonging to the class of sulfonamides commonly used against gram-postive and gram-negative microorganisms in humans and veterinary medication. Its mode of action involves inhibiting the multiplication of bacteria as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfadiazine may be used as an internal standard for the determination of sulfapyridine in biological samples using high-performance liquid chromatography technique.

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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High-performance liquid chromatographic method for determination of sulfapyridine in human saliva using post-column, in-line derivatization with fluorescamine
Sista.S.H, et al.
Journal of Chromatography. B, Biomedical Applications, 273(2), 103-106 (1983)
Eco-toxic effects of sulfadiazine sodium, sulfamonomethoxine sodium and enrofloxacin on wheat, Chinese cabbage and tomato
Ecotoxicology (London, England), 18(7), 878-885 (2009)
Drugs: Synonyms and Properties (2017)
Chun-Xue Zhou et al.
Antimicrobial agents and chemotherapy, 63(10) (2019-08-07)
In this study, we analyzed the global metabolomic changes associated with Toxoplasma gondii infection in mice in the presence or absence of sulfadiazine sodium (SDZ) treatment. BALB/c mice were infected with T. gondii GT1 strain and treated orally with SDZ
Yves du Toit et al.
Frontiers in microbiology, 11, 216-216 (2020-03-05)
Many pests and pathogens threaten Eucalyptus plantations. The study of defense responses in this economically important wood and fiber crop enables the discovery of novel pathways and genes, which may be adopted to improve resistance. Various functional genomics experiments have

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