K2012

Ketoprofen

meets USP testing specifications

• Synonym(s): 2-(3-Benzoylphenyl)propionic acid
• Empirical Formula (Hill Notation): C₁₆H₁₄O₃
• CAS Number: 22071-15-4
• Molecular Weight: 254.28
• NACRES: NA.21
• PubChem Substance ID: 24896217
• UNSPSC Code: 41116107
• EC Number: 244-759-8
• MDL number: MFCD00055790

Properties

• Quality Segment: 200
• agency: USP/NF, meets USP testing specifications
• form: solid
• application(s): pharmaceutical (small molecule)
• SMILES string: CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2
• InChI: 1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)
• InChI key: DKYWVDODHFEZIM-UHFFFAOYSA-N
• Gene Information: human ... ALB(213), IL8RA(3577), PTGS1(5742), PTGS2(5743)

Description

Application

• A strong, silk protein-inspired tissue adhesive with an enhanced drug release mechanism for transdermal drug delivery.: Although not exclusively focused on ketoprofen, this study details a novel adhesive for transdermal delivery, highlighting methods that could be adapted for enhancing the delivery of ketoprofen, thus being of interest to biochemists specializing in transdermal drug formulations (Fang et al., 2024).

Biochem/physiol Actions

Non-steroidal anti-inflammatory compound that is selective for COX-1.

Safety Information

• Pictograms: GHS06,GHS09
• Signal Word: Danger
• Hazard Codes: H301,H315,H319,H400
• Precautionary Statements: P264 - P273 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges