C6852

L-Cysteine hydrochloride monohydrate

98.5-101.0% dry basis, suitable for cell culture, non-animal source, meets EP, USP testing specifications

• Synonym(s): L-Cysteine hydrochloride hydrate (1:1:1)
• Linear Formula: HSCH₂CH(NH₂)COOH · HCl · H₂O
• CAS Number: 7048-04-6
• Molecular Weight: 175.63
• Beilstein: 5158059
• EC Number: 200-157-7
• MDL number: MFCD00065606
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24892902
• NACRES: NA.26

Properties

• Product Name: L-Cysteine hydrochloride monohydrate, from non-animal source, suitable for cell culture, meets EP, USP testing specifications
• biological source: non-animal source
• Quality Level: 300
• Agency: meets EP testing specifications; meets USP testing specifications
• Assay: 98.5-101.0% dry basis
• form: powder or crystals
• optical activity: [α]20/D 6.1 to 7.8°, c = 8 in 1 M HCl; [α]25/D 5.7 to 6.8°, c = 8 in HCl (6 N)
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white
• solubility: water: 1 g/10 mL, clear, colorless
• cation traces: Fe: ≤10 ppm; NH₄⁺: ≤0.02%
• application(s): pharmaceutical (small molecule)
• functional group: (sulfhydryl)
• storage temp.: room temp
• SMILES string: O.Cl.N[C@@H](CS)C(O)=O
• InChI: 1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1
• InChI key: QIJRTFXNRTXDIP-JIZZDEOASA-N

Description

General description

L-Cysteine hydrochloride, commonly referred to as Cysteine HCl, is a vital component in biochemical research due to its versatile roles. Derived from the naturally occurring amino acid L-cysteine, this compound plays a crucial part in redox reactions, protein structure, cell culture, and antioxidant activity. Cysteine HCl functions as a reducing agent and a nucleophile in redox reactions. Additionally, it serves as a precursor to glutathione, a potent cellular antioxidant. Its significance extends to protein structure, where it contributes to the formation of disulfide bonds that stabilize protein structures. Cysteine HCl also supports cell growth and viability in cell culture applications. Its widespread applications encompass diverse areas of biochemical research, including redox biology, protein biochemistry, cell biology, and antioxidant investigations.

Application

L-Cysteine hydrochloride monohydrate has been used as a component of yeast dropout media for culturing yeasts.[1] It has also been used as a component of differential reinforced clostridial broth (DRCM) for the isolation of clostridia.[1]

Biochem/physiol Actions

Cysteine (Cys) is a sulfur-containing amino acid[2] that modulates metabolism for growth, reproduction and immunity. It provides the disulfide linkage in proteins and in involved in the transport of sulfur. Cysteine is involved in the formation of hydrogen sulfide that functions as a signaling molecule.[3] Cys residues are present at the catalytic sites of various enzymes.[4]

NMDA glutamatergic receptor antagonist.

Features and Benefits

• Suitable for Cell Culture and Biochemical research
• High-quality compound suitable for multiple research applications

Other Notes

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Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves