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Luteolin

primary reference standard

Synonym(s):

3′,4′,5,7-Tetrahydroxyflavone

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About This Item

Empirical Formula (Hill Notation):
C15H10O6
CAS Number:
491-70-3
Molecular Weight:
286.24
Beilstein:
292084
EC Number:
207-741-0
MDL number:
MFCD00017309
UNSPSC Code:
85151701
PubChem Substance ID:
329747828
NACRES:
NA.24

grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

mp

~330 °C (lit.)

application(s)

food and beverages

SMILES string

Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccc(O)c(O)c3

InChI

1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H

InChI key

IQPNAANSBPBGFQ-UHFFFAOYSA-N

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General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Reference Standard in the analysis of herbal medicinal products

Other Notes

This compound is commonly found in plants of the genus: achillea

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
HWI03169-1
HWI03169
HWI02485-1
HWI02485
HWI02293

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Theoharis C Theoharides et al.
Advances in experimental medicine and biology, 601, 423-430 (2007-08-24)
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) mainly mediated by Th1, but recent evidence indicates that Th2 T cells, mostly associated with allergic reactions, are also involved. Mast cells are involved in allergic and
Yong Lin et al.
Current cancer drug targets, 8(7), 634-646 (2008-11-11)
Luteolin, 3',4',5,7-tetrahydroxyflavone, is a common flavonoid that exists in many types of plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been used in Chinese traditional medicine for treating various diseases such as hypertension, inflammatory disorders, and
Sung Wook Park et al.
Investigative ophthalmology & visual science, 53(12), 7718-7726 (2012-10-27)
Oxidative stress-induced vascular endothelial growth factor (VEGF) is thought to play a critical role in the pathogenesis of retinopathy of prematurity (ROP). This study was performed to investigate the anti-angiogenic effect of luteolin against reactive oxygen species (ROS)-induced retinal neovascularization.
Günter Seelinger et al.
Planta medica, 74(14), 1667-1677 (2008-10-22)
Luteolin is a flavone which occurs in medicinal plants as well as in some vegetables and spices. It is a natural anti-oxidant with less pro-oxidant potential than the flavonol quercetin, the best studied flavonoid, but apparently with a better safety
Chithan Kandaswami et al.
In vivo (Athens, Greece), 19(5), 895-909 (2005-08-16)
The flavonoids are polyphenolic compounds found as integral components of the human diet. They are universally present as constituents of flowering plants, particularly of food plants. The flavonoids are phenyl substituted chromones (benzopyran derivatives) consisting of a 15-carbon basic skeleton
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