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H-096

Supelco

17α-Hydroxyprogesterone-d8 (2,2,4,6,6,21,21,21-d8)

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

17alpha-Hydroxyprogesterone-D8 (2,2,4,6,6,21,21,21-D8) solution

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About This Item

Empirical Formula (Hill Notation):
C21H22O3D8
CAS Number:
850023-80-2
Molecular Weight:
338.51
EC Number:
200-659-6
MDL number:
MFCD03428149
UNSPSC Code:
41116107
PubChem Substance ID:
329815143
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

[2H]C1=C2C([2H])([2H])C[C@@H]3[C@H](CC[C@@]4(C)[C@H]3CC[C@]4(O)C(=O)C([2H])([2H])[2H])[C@@]2(C)CC([2H])([2H])C1=O

InChI

1S/C21H30O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h12,16-18,24H,4-11H2,1-3H3/t16-,17+,18+,19+,20+,21+/m1/s1/i1D3,4D2,6D2,12D

InChI key

DBPWSSGDRRHUNT-LDLLURODSA-N

General description

100 μg/mL in Methanol A stable labeled internal standard suitable for quantitation of 17α-Hydroxyprogesterone levels in LC-MS/MS testing assays for newborn screening or endocrinology.

Application


  • Dried blood spot sampling of testosterone microdosing in healthy females: Demonstrates the application of 17 alpha-Hydroxyprogesterone-d8 in mass spectrometry standards to ensure precision in microdosing studies, highlighting its crucial role in developing therapeutic strategies for hormone balance (Desai et al., 2024).

  • Calcium complexation by steroids involved in steroidogenesis: Features the use of 17 alpha-Hydroxyprogesterone-d8 in studying the interactions of steroids with minerals, providing a fundamental understanding of biochemical pathways crucial for hormone synthesis research (Siless and Cabrera, 2024).

  • Multiplexed Serum Steroid Profiling Reveals Metabolic Signatures of Subtypes in Congenital Adrenal Hyperplasia: Utilizes 17 alpha-Hydroxyprogesterone-d8 as part of a comprehensive panel in mass spectrometry to differentiate subtypes of adrenal hyperplasia, showcasing its application in detailed biochemical profiling (Shim et al., 2023).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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