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860382P

Avanti

16:0 PG-d62

Avanti Research™ - A Croda Brand 860382P, powder

Synonym(s):

1,2-dipalmitoyl-d62-sn-glycero-3-[phospho-rac-(1-glycerol)] (sodium salt)

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About This Item

Empirical Formula (Hill Notation):
C38H12O10PNaD62
CAS Number:
326495-46-9
Molecular Weight:
807.33
UNSPSC Code:
12352100
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (860382P-10mg)
pkg of 1 × 100 mg (860382P-100mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860382P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)COC(C([2H])([2H])

General description

1,2-dipalmitoyl-d62-sn-glycero-3-[phospho-rac-(1-glycerol)] (16:0 PG-d62) is a deuterated phosphoglycerol (PG) wherein 62 protons in dipalmitoyl are replaced by deuterium.
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Application

1,2-dipalmitoyl-d62-sn-glycero-3-[phospho-rac-(1-glycerol)] (16:0 PG-d62) has been used:
  • in lipid bilayer to study its interaction with alamethicin
  • in the preparation of deuterated liposomes to study its interaction with 15N-labeled MapZcyto in solid-state nuclear magnetic resonance (NMR)
  • as a component of lipid bilayer to study its molecular-level interactions with antimicrobial peptides (AMPs) using sum frequency generation (SFG) vibrational spectroscopy

Packaging

5 mL Amber Glass Screw Cap Vial (860382P-100mg)
5 mL Amber Glass Screw Cap Vial (860382P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tomas Hosek et al.
Scientific reports, 10(1), 4051-4051 (2020-03-07)
MapZ localizes at midcell and acts as a molecular beacon for the positioning of the cell division machinery in the bacterium Streptococcus pneumoniae. MapZ contains a single transmembrane helix that separates the C-terminal extracellular domain from the N-terminal cytoplasmic domain.
Lauren Soblosky et al.
Chemistry and physics of lipids, 187, 20-33 (2015-02-25)
Supported lipid bilayers are used as a convenient model cell membrane system to study biologically important molecule-lipid interactions in situ. However, the lipid bilayer models are often simple and the acquired results with these models may not provide all pertinent
Shuji Ye et al.
The journal of physical chemistry. B, 114(9), 3334-3340 (2010-02-19)
Structures of membrane-associated peptides and molecular interactions between peptides and cell membrane bilayers govern biological functions of these peptides. Sum frequency generation (SFG) vibrational spectroscopy has been demonstrated to be a powerful technique to study such structures and interactions at
Chu Wang et al.
Langmuir : the ACS journal of surfaces and colloids, 36(6), 1615-1622 (2020-01-23)
Body fluids flow all over the body and affect the biological processes at biointerfaces. To simulate such a case, sum frequency generation (SFG) vibrational spectroscopy and a self-designed microfluidic chip were combined together to investigate the interaction between a pH-responsive

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