SRP8008

FTO mouse

recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE)

• Synonym(s): EC 1.14.11, FATSO, Fat mass and obesity-associated protein, Preadipocyte factor 1
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• biological source: mouse
• recombinant: expressed in E. coli
• tag: His tagged
• Assay: >90% (SDS-PAGE)
• form: liquid
• mol wt: ~55 kDa by SDS-PAGE
• packaging: pkg of 10 μg
• storage condition: avoid repeated freeze/thaw cycles
• concentration: ≥0.2 mg/mL
• impurities: <1 EU/μg endotoxin, tested
• color: clear
• UniProt accession no.: Q8BGW1
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: mouse ... Fto(26383)

Description

General description

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ′fused toes′ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

Physical form

Solution in 55 mM TRIS-HCl, pH 8.2, containing 150 mM NaCl.

Other Notes

Mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable