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SRP0377

Sigma-Aldrich

PLU-1 human

recombinant, expressed in baculovirus infected Sf9 cells, ≥55% (SDS-PAGE)

Synonym(s):

JARID1B, KDM5B, lysine (K)-specific demethylase 5B

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About This Item

UNSPSC Code:
12352200

biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

Assay

≥55% (SDS-PAGE)

form

aqueous solution

mol wt

88 kDa

packaging

pkg of 20 μg

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... KDM5B(10765)

General description

Human Plu-1, also known as JARID1B and KDM5B (GenBank Accession No. NM_006618), amino-acids 2-751 with N-terminal HIS-FLAG-tag, MW=88 kDa, expressed in Sf9 cells via a Baculovirus expression system.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Angela Barrett et al.
International journal of cancer, 121(2), 265-275 (2007-03-22)
The PLU-1/JARID1B nuclear protein, which is expressed in a high proportion of breast cancers, but shows restricted expression elsewhere, belongs to the ARID family of proteins, known to play important roles in development, differentiation, transcriptional regulation and chromatin remodeling. PLU-1/JARID1B
Kenichi Yamane et al.
Molecular cell, 25(6), 801-812 (2007-03-17)
Posttranslational modification of chromatin by histone methylation has wide-ranging effects on nuclear function, including transcriptional regulation, maintenance of genome integrity, and epigenetic inheritance. The enzymes utilized to place histone methylation marks are well characterized, but the identity of a histone

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