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S0945

Sigma-Aldrich

Anti-Somatostatin Receptor Type 4 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-SSTR4

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

availability

not available in Japan

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 3 μg/mL using human pancreas, Islets of Langerhans

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SSTR4(6754)
mouse ... Sstr4(20608)
rat ... Sstr4(25555)

Immunogen

synthetic peptide corresponding to the N-terminal extracellular domain of human somatostatin receptor type 4, conjugated to KLH. The immunizing peptide has 50% homology with the rat gene and 38% homology with the mouse gene.

Physical form

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Zakariae Bram et al.
The Journal of clinical endocrinology and metabolism, 99(5), E891-E901 (2014-02-12)
Somatostatin (SST) receptors (SSTRs) are expressed in a number of tissues, including the adrenal cortex, but their role in cortisol secretion has not been well characterized. The objective of the study was to investigate the expression of SSTRs in the
J Van Op den Bosch et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 19(7), 596-606 (2007-06-27)
Despite our knowledge of somatostatin (SOM) in gastrointestinal functions, little information is available on the SOM receptors (SSTRs) mediating these effects. This study focussed on the expression of SSTRs in non-inflamed and Schistosoma mansoni-infected murine ileum using immunocytochemistry, reverse transcriptase
Joeri Van Op den Bosch et al.
Journal of cellular and molecular medicine, 13(9B), 3283-3295 (2009-05-12)
The recently suggested pivotal role of somatostatin (SOM) receptor 4 (SSTR4) in inflammation and nociception in several non-intestinal organs and in gastrointestinal (GI) physiology, necessitates exploration of the role of SSTR4 in GI pathophysiology. Therefore, the role of SSTR4 in
Joeri Van Op den bosch et al.
American journal of physiology. Gastrointestinal and liver physiology, 297(2), G406-G417 (2009-05-30)
The course of intestinal inflammatory responses is tightly coordinated by the extensive communication between the immune system and the enteric nervous system, among which the bidirectional mast cell-neuron interaction within the intestinal wall plays a prominent role. Recent research suggests
J Yamamoto et al.
British journal of cancer, 110(9), 2232-2245 (2014-04-20)
Malignant pleural mesothelioma (MPM) is an aggressive neoplasm arising from mesothelial lining of pleura. CD26 molecules preferentially expressed on epithelioid type of MPM. This study investigates the molecular mechanisms of CD26 regulating MPM cells in vitro and in vivo. Biochemical

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