M3316

Myoseverin B

≥97% (HPLC)

• Synonym(s): 2,6-Bis(4-methoxybenzylamino)-9-cyclohexylpurine
• Empirical Formula (Hill Notation): C₂₇H₃₂N₆O₂
• CAS Number: 361431-27-8
• Molecular Weight: 472.58
• MDL number: MFCD08276922
• UNSPSC Code: 12352200
• PubChem Substance ID: 24724538
• NACRES: NA.77

Properties

• Assay: ≥97% (HPLC)
• solubility: DMSO: soluble; H₂O: insoluble
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: COc1ccc(CNc2nc(NCc3ccc(OC)cc3)c4ncn(C5CCCCC5)c4n2)cc1
• InChI: 1S/C27H32N6O2/c1-34-22-12-8-19(9-13-22)16-28-25-24-26(33(18-30-24)21-6-4-3-5-7-21)32-27(31-25)29-17-20-10-14-23(35-2)15-11-20/h8-15,18,21H,3-7,16-17H2,1-2H3,(H2,28,29,31,32)
• InChI key: ZUZXYJOSNSTJMU-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Myoseverin, a new microtubule-binding molecule, acts reversibly on myoblast proliferation without the cytotoxic effects displayed by nonpurine-based microtubule-disrupting molecules, like taxol, vinblastine, nocodazole. Myoseverin can be effectively used for the inhibition of new vessel growth by inhibiting endothelial cell function and differentiation of progenitor cells.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves