Skip to Content
Merck
All Photos(2)

Documents

M0132

Sigma-Aldrich

5-Methyltetrahydrofolic acid disodium salt

≥88% (UV-vis)

Synonym(s):

5-Methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid disodium salt, 5-Methyl-THF

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C20H23N7Na2O6
CAS Number:
68792-52-9
Molecular Weight:
503.42
MDL number:
MFCD00070147
UNSPSC Code:
12352204
PubChem Substance ID:
24896534
NACRES:
NA.32

Assay

≥88% (UV-vis)

form

powder

solubility

water: 25 mg/mL

shipped in

wet ice

storage temp.

−20°C

SMILES string

[Na+].[Na+].CN1C(CNc2ccc(cc2)C(=O)N[C@H](CCC([O-])=O)C([O-])=O)CNc3nc(N)nc(O)c13

InChI

1S/C20H25N7O6.2Na/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29;;/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31);;/q;2*+1/p-2

InChI key

KKIWVYLOTHCGRV-UHFFFAOYSA-L

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

5-Methyl-THF acts as both cofactor and substrate in the regeneration of methionine from homocysteine through the action of 5-methyl-THF-homocysteine S-methyltransferase.

Packaging

Sealed ampule

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Sharareh Rezaeian et al.
International journal of medicinal mushrooms, 23(2), 57-66 (2021-02-28)
Edible mushrooms are among food sources containing natural folate compounds. However, little is known about how the content of folates in edible mushrooms may be improved. This study aimed to enrich Flammulina velutipes with higher levels of folates and to
Joachim Michael Matz et al.
Cell reports, 26(2), 356-363 (2019-01-10)
Folate metabolism is essential for DNA synthesis and a validated drug target in fast-growing cell populations, including tumors and malaria parasites. Genome data suggest that Plasmodium has retained its capacity to generate folates de novo. However, the metabolic plasticity of

Articles

Folic Acid Metabolism in Cancer

Biofiles reviews innovative technologies for cancer research, reflecting the complexity of the disease.

Folic Acid Metabolism in Cancer

Cancer research innovations address the complexity of the disease, providing advanced technologies for varied applications.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service