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EMU085211

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Ahr

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GCAGGATTTGCAAGAAGGAGAGTTCTTGTTACAGGCGCTGAATGGCTTTGTGCTGGTTGTCACAGCAGATGCCTTGGTCTTCTATGCTTCCTCCACTATCCAAGATTACCTGGGCTTTCAGCAGTCTGATGTCATCCATCAGAGCGTATATGAGCTCATCCATACAGAAGACCGGGCGGAATTCCAGCGCCAGCTTCACTGGGCTCTAAACCCAGACTCTGCACAAGGAGTGGACGAAGCCCATGGCCCTCCACAGGCAGCAGTCTATTATACCCCAGACCAGCTTCCTCCAGAGAACGCTTCTTTCATGGAGAGGTGCTTCAGGTGCCGGCTGAGGTGCCTGCTGGATAATTCATCTGGTTTTCTGGCAATGAATTTCCAAGGGAGGTTAAAGTATCTTCATGGACAGAACAAGAAAGGGAAGGACGGAGCGCTGCTTCCTCCACAACTGGCTTTGTTTGCAATAGCTACTCCACTTCAGCCACCCTCCATCCTGGAAATTCGAA

Ensembl | mouse accession no.

ENSMUSG00000019256

NCBI accession no.

NM_013464

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... AHR(11622) , Ahr(11622)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mariko Takami et al.
Journal of immunology (Baltimore, Md. : 1950), 195(6), 2520-2523 (2015-08-16)
The immunoregulatory functions of vitamin D have been well documented in various immunological disorders, including multiple sclerosis, arthritis, and asthma. IL-10 is considered a chief effector molecule that promotes the vitamin D-induced immunosuppressive states of T cells and accessory cells.
Travis B Salisbury et al.
Biochemical pharmacology, 91(3), 390-399 (2014-06-28)
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that upon activation by the toxicant 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD) stimulates gene expression and toxicity. AHR is also important for normal mouse physiology and may play a role in cancer progression

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