C5135

Castor Oil, Ethoxylated

pH range 6.0-8.0

• Synonym(s): Cremophor^® EL, EL, Macrogolglycerol ricinoleate, PEG-35 castor oil, Polyoxyl-35 castor oil
• CAS Number: 61791-12-6
• MDL number: MFCD00130879
• UNSPSC Code: 12161902
• NACRES: NA.25

Properties

• description: non-ionic
• form: liquid
• mol wt: ~2500 g/mol
• pH range: 6.0-8.0
• HLB: 12 - 14
• application(s): sample preservation
• InChI: 1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)
• InChI key: JMNCUXPHXKHBPY-UHFFFAOYSA-N

Description

General description

Castor Oil, Ethoxylated is a nonionic solubilizer and emulsifier made by reacting castor oil with ethylene oxide. It is a pale yellow oily liquid that is clear at temperatures above 26°C. It has a faint but characteristic odour.

Castor Oil, Ethoxylated is polyethylene oxide surfactant and is viscous in nature. It has a hydrophobic-lipophilic balance value in the range of 12-14.

Application

Castor Oil, Ethoxylated has been used as a detergent to improve the solubility of dye and to increase the transmembrane permeation. It has been used as a vehicle for drug/stimulant delivery in cells.

Biochem/physiol Actions

Castor Oil, Ethoxylated is used in lipid-based formulations for drugs and solubilization of cosmetics. Castor Oil, Ethoxylated is suitable for the production of semi-solid and liquid formulations of water-insoluble actives and other hydrophobic compounds. Due to its emulsification functionality, it finds application in biological membrane- based drug transport studies.

Other Notes

A derivative of castor oil and ethylene oxide.

Legal Information

Cremophor is a registered trademark of BASF SE

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 494.6 °F - Not applicable
• Flash Point(C): 257 °C - Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves