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51292

Sigma-Aldrich

Hemoglobin from bovine blood

≥85% (HPCE)

Synonym(s):

Bovine hemoglobin, Hb, Methemoglobin

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About This Item

CAS Number:
9008-02-0
MDL number:
MFCD00131282
UNSPSC Code:
12352202
eCl@ss:
42030116

biological source

bovine blood

Assay

≥85% (HPCE)
~95% protein basis

mol wt

Mr ~64500

loss

≤5% loss on drying

UniProt accession no.

P01966
P02070
P02081
P06642
P06643

storage temp.

2-8°C

Gene Information

cow ... HBA1(281221) , HBB(280813) , HBE2(513240) , HBE4(513108) , HBG(511735) , alpha globin(512439)

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Application

The solubility of α-elastin has been applied to construction of elastin-mimetic biomaterials.

Biochem/physiol Actions

Oxygen transporter, NO scavenger
Oxygen transporter. The Fe2+/Fe3+ balance is a physiological indicator of blood oxygenation; deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.

Caution

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
STBD2586V
321553/1
317155/1

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Masayo Sawa et al.
Neuropsychobiology, 67(2), 103-110 (2013-02-15)
Only a few studies have examined the relationships between affective symptoms, cognitive function (e.g. verbal fluency), quality of life (QOL), and brain activation in a nonclinical population. The aim of the present study was to assess these relationships and examine
N F Schreiter et al.
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 185(4), 358-366 (2013-03-16)
To investigate whether changes in hemodynamics induced by Valsalva maneuver can be exploited for detecting and characterizing breast lesions by optical mammography. 30 women underwent optical imaging of the breast using a DYNOT 232 system and performing Valsalva maneuvers prior
Toru Yamada et al.
PloS one, 7(11), e50271-e50271 (2012-11-28)
In conventional functional near-infrared spectroscopy (fNIRS), systemic physiological fluctuations evoked by a body's motion and psychophysiological changes often contaminate fNIRS signals. We propose a novel method for separating functional and systemic signals based on their hemodynamic differences. Considering their physiological
Konstantinos Balaskas et al.
The British journal of ophthalmology, 97(5), 558-560 (2012-11-10)
This study examines the differences in spectral absorption properties between the maculae of patients with active neovascular macular degeneration and those with early age related maculopathy (ARM). Patients attending for management of neovascular age related macular degeneration (AMD) underwent multispectral
Enrico Bucci et al.
Biochemistry, 52(24), 4149-4156 (2013-05-29)
Hill's plots of oxygen binding isotherms reveal the presence of a transition between two different oxygen affinities at the beginning and end of the isotherm. They correspond to the two conformations anticipated by the MWC model, namely, the T and
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Chromatograms

application for HPLC

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