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P4554

Supelco

Proparacaine hydrochloride

analytical standard

Synonym(s):

Proxymetacaine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C16H26N2O3 · HCl
CAS Number:
5875-06-9
Molecular Weight:
330.85
EC Number:
227-541-7
MDL number:
MFCD00083467
UNSPSC Code:
41116107
PubChem Substance ID:
329820210
NACRES:
NA.24

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.CCCOc1ccc(cc1N)C(=O)OCCN(CC)CC

InChI

1S/C16H26N2O3.ClH/c1-4-10-20-15-8-7-13(12-14(15)17)16(19)21-11-9-18(5-2)6-3;/h7-8,12H,4-6,9-11,17H2,1-3H3;1H

InChI key

BFUUJUGQJUTPAF-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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General description

Proparacaine hydrochloride is a topical ocular anesthetic, which is commonly used in pediatric patients.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Topical ophthalmic anesthetic

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
070H0599
070H05991

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Michael J Davis et al.
Retina (Philadelphia, Pa.), 32(4), 701-705 (2012-01-28)
To determine whether there is a difference in anesthetic effect between topical proparacaine drops, 4% lidocaine solution, or 3.5% lidocaine gel, and whether this has an impact on the overall injection experience. One hundred and twenty sequential patients undergoing intravitreal
Takefumi Yamaguchi et al.
Investigative ophthalmology & visual science, 55(11), 7457-7466 (2014-10-18)
We investigated bilateral tear cytokine levels in patients with unilateral bacterial keratitis (BK) as associated with in vivo confocal microscopic (IVCM) alterations in corneal nerves and dendritiform immune cells (DCs). A total of 54 (13 BK, 13 contralateral, 28 healthy
Pediatric Cataract Surgery: Techniques, Complications, and Management (2005)
Lana Rifkin et al.
Retina (Philadelphia, Pa.), 32(4), 696-700 (2011-11-16)
To determine factors associated with patients' comfort during routine in-office intravitreal injection. Sixty patients receiving intravitreal injections over 15 months for macular edema because of diabetes, age-related macular degeneration, or retinal vein occlusion who were randomized into 3 groups to
Applied Pharmacology for Veterinary Technicians (2009)
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