924377

Palladium(II) Acetate ChemBeads

• Synonym(s): Acetic acid palladium salt, Bis(acetato)palladium, Diacetatopalladium, Diacetoxypalladium
• Linear Formula: Pd(OCOCH₃)₂
• CAS Number: 3375-31-3
• MDL number: MFCD00012453
• UNSPSC Code: 12352302
• NACRES: NA.82

Properties

• form: solid
• Quality Level: 100
• composition: ~ 4 wt.% loading of catalyst
• reaction suitability: core: palladium; reaction type: Buchwald-Hartwig Cross Coupling Reaction; core: palladium; reaction type: Heck Reaction; core: palladium; reaction type: Hiyama Coupling; core: palladium; reaction type: Negishi Coupling; core: palladium; reaction type: Sonogashira Coupling; core: palladium; reaction type: Stille Coupling; core: palladium; reaction type: Suzuki-Miyaura Coupling; reaction type: Cross Couplings; reagent type: catalyst
• InChI: 1S/2C2H4O2.Pd/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2
• InChI key: YJVFFLUZDVXJQI-UHFFFAOYSA-L

Description

General description

Palladium(II) acetate is a homogenous oxidation catalyst. It participates in the activation of alkenic and aromatic compounds towards oxidative inter- and intramolecular nucleophilic reactions. Crystals of palladium(II) acetate have a trimeric structure, having symmetry D_3h. Each of the palladium atoms in the crystals are joined to the other two by double acetate bridges. Microencapsulation of palladium(II) acetate in polyurea affords polyurea-encapsulated palladium(II) acetate. It is a versatile heterogeneous catalyst for various phosphine-free cross-coupling reactions. It participates as catalyst in the Heck coupling reaction of pthalides with different alkenes.

Application

Catalyst for an intramolecular coupling of aryl bromides with alcohols giving 1,3-oxazepines. Preparation of cyclic ureas via palladium-catalyzed intramolecular cyclization.

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

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For larger scale uses, product also available in powdered form (205869) & (520764)

Other Notes

High-Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Beads

Versatile Methods to Dispense Sub-Milligram Quantities of Solids using Chemical Coated Beads for High-Throughput Experimentation

ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand

Safety Information

• Pictograms: GHS05,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H317,H318,H410
• Precautionary Statements: P261 - P272 - P273 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1A
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable