GF426
IL-28B, Human
HumanKine®, recombinant, Xeno-free, >95% (SDS-PAGE), suitable for cell culture
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.75
General description
HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
IL-28B is a cytokine distantly related to type I interferons and the IL-10 family. IL-28A, IL-28B, and IL-29 are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Quality
Bioactivity assay: Determined by the dose dependent protection of the cytopathic effect on A549 cells (human lung
adenocarcinoma epithelial cell line) that were challenged with encephalomyocarditis (EMC) virus. ED50 is typically 0.1-1 ng/ml.
adenocarcinoma epithelial cell line) that were challenged with encephalomyocarditis (EMC) virus. ED50 is typically 0.1-1 ng/ml.
HumanKine IL-28B is manufactured using all non-animal reagents and is considered Xeno-Free
Physical form
Product is presented in PBS and filtered through a 0.2 micron filter before lyophilization.
Storage and Stability
Store at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
Legal Information
HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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