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DR1041

Sigma-Aldrich

Anti-TIP60 Rabbit pAb

liquid, Calbiochem®

Synonym(s):

Anti-HIV-1 Tat interactive protein, Anti-cPLA2-interaction protein

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KAT5(10524)

General description

Rabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~60 kDa TIP60 protein.
Recognizes the ~60 kDa TIP60 protein in Saos-2 cells.
This Anti-TIP60 Rabbit pAb is validated for use in Immunoblotting, Immunoprecipitation for the detection of TIP60.

Immunogen

recombinant, human TIP60 protein

Application


Immunoblotting (1:3000)
Immunoprecipitation (1:100)

Warning

Toxicity: Standard Handling (A)

Analysis Note

Positive Control
Saos-2 cells

Other Notes

Murr, R., et al. 2006. Nat. Cell Biol.8, 91.
Sykes, S.M., et al. 2006. Mol. Cell24, 841.
Tang, Y., et al. 2006. Mol. Cell24, 827.
Frank, S.R., et al. 2003. EMBO Rep.6, 575.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sokhna M S Yakhine-Diop et al.
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Virology, 499, 178-184 (2016-09-25)
The adenovirus E1A 243R oncoprotein targets TRRAP, a scaffold protein that assembles histone acetyltransferase (HAT) complexes, such as the NuA4/Tip60 complex which mediates transcriptional activity of the proto-oncogene MYC and helps determine the cancer cell phenotype. How E1A transforms cells
Kristin A Krukenberg et al.
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Poly(ADP-ribose) polymerases (PARPs) catalyze poly(ADP-ribose) addition onto proteins, an important posttranslational modification involved in transcription, DNA damage repair, and stem cell identity. Previous studies established the activation of PARP1 in response to DNA damage, but little is known about PARP1
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Global histone hyperacetylation is suggested to play a critical role for replacement of histones by transition proteins and protamines to compact the genome during spermiogenesis. However, the underlying mechanisms for hyperacetylation-mediated histone replacement remains poorly understood. Here, we report that

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