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ABN12

Sigma-Aldrich

Anti-Neuropeptide S Receptor Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Neuropeptide S receptor, G-protein coupled receptor 154

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat, human

technique(s)

immunohistochemistry: suitable (paraffin)

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... NPSR1(387129)

General description

Neuropeptide S receptor (NPSR) is alternatively known as G-protein coupled receptor 15. NPSR is a multi-pass cell membrane protein that functions as a vasopressin/oxytocin receptor in the G-protein coupled receptor 1 family. As a receptor for neuropeptide S, it is thought to mediate its action, such as inhibitory effects, on cell growth.

Specificity

This antibody recognizes the C-terminus of Neuropeptide S Receptor.

Immunogen

Epitope: C-terminus
Recombinant protein corresponding to the C-terminus of rat Neuropeptide S Receptor.

Application

Imunnohistochemistry Analysis: A 1:500 dilution of this antibody detected Neuropeptide S Receptor in rat and human cerebellum tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling
This Neuropeptide S Receptor antibody is validated for use in IHC for the detection of the Neuropeptide S Receptor protein.

Quality

Evaluated by Immunohistochemistry in rat and human cerebellum tissue.

Imunnohistochemistry Analysis: A 1:2,000 dilution of this antibody detected Neuropeptide S Receptor in rat cerebellum tissue.

Target description

65 kDa calculated

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Rat cerebellum tissue

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mehmet Bülbül et al.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 31(1), 65-72 (2020-02-06)
The novel brain peptide neuropeptide-S (NPS) is produced exclusively by a small group of cells adjacent to the noradrenergic locus coeruleus. The NPSR mRNA has been detected in several brain areas involved in stress response and autonomic outflow, such as

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