8.18831

Diisobutyl ketone

for synthesis

• Synonym(s): Diisobutyl ketone, Di-iso-butyl ketone, 2,6-Dimethyl-4-heptanone, Isobutyl ketone
• Linear Formula: (CH₃)₂CHCH₂COCH₂CH(CH₃)₂
• CAS Number: 108-83-8
• Molecular Weight: 142.24
• MDL number: MFCD00008940
• UNSPSC Code: 12352115
• EC Index Number: 203-620-1
• NACRES: NA.22

Properties

• vapor pressure: 1.6 hPa ( 20 °C)
• Quality Level: 200
• form: liquid
• autoignition temp.: 345 °C
• potency: 5750 mg/kg LD₅₀, oral (Rat); 16000 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 0.8-6.2 % (v/v)
• bp: 163-173 °C/1013 hPa
• mp: -41 °C
• transition temp: flash point 47 °C
• solubility: 0.5 g/L
• density: 0.81 g/cm³ at 20 °C
• storage temp.: 2-30°C
• InChI: 1S/C9H18O/c1-7(2)5-9(10)6-8(3)4/h7-8H,5-6H2,1-4H3
• InChI key: PTTPXKJBFFKCEK-UHFFFAOYSA-N

Description

Application

• Fast, selective, and sensitive analysis of low-abundance peptides in human plasma by electromembrane extraction.: This research demonstrates the application of diisobutyl ketone in electromembrane extraction techniques, significantly enhancing the selectivity and sensitivity of peptide analysis. This method holds potential for advancing proteomic studies and clinical diagnostics (Balchen M et al., 2012).


• Direct determination of bromine in plastics by electrothermal vaporization/inductively coupled plasma mass spectrometry using a tungsten boat furnace vaporizer and an exchangeable sample cuvette system.: Highlights the role of diisobutyl ketone in preparing plastic samples for bromine analysis, addressing significant challenges in environmental monitoring and recycling processes (Okamoto Y et al., 2010).


• Flow injection wetting-film extraction system for flame atomic absorption spectrometric determination of cadmium in environmental waters.: Discusses a novel method involving diisobutyl ketone for the extraction of cadmium from environmental waters, contributing to enhanced detection capabilities in pollution monitoring and water safety (Adam IS et al., 2009).


• [Thermal desorption gas chromatography for determination of diisobutyl ketone in air of working places].: This study uses diisobutyl ketone in a thermal desorption gas chromatography method to measure workplace air quality, essential for occupational health and safety regulations in industrial environments (Chen W et al., 2008).


• Synthesis of the O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine oximes of selected carbonyl compounds and their determination by liquid chromatography with ultraviolet detection.: Research on diisobutyl ketone involves its use in synthesizing chemical derivatives for improved UV detection in liquid chromatography, enhancing analytical accuracy in chemical and pharmaceutical analyses (Wiesenthal K et al., 2000).

Analysis Note

Sum of 2,6-Dimethyl-4-heptanone and 2,4-Dimethyl-6-heptanone (GC, area%): ≥ 96.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.807 - 0.811
Identity (IR): passes test

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Warning
• Hazard Statements: H226 - H335
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 3 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 120.2 °F - closed cup
• Flash Point(C): 49 °C - closed cup