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07-002

Sigma-Aldrich

Anti-p67-phox Antibody

serum, Upstate®

Synonym(s):

Anti-NCF-2, Anti-NOXA2, Anti-P67-PHOX, Anti-P67PHOX

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... NCF2(4688)

Specificity

p67-phox

Immunogen

GST fusion protein corresponding to full-length human p67-phox.

Application

Research Category
Neuroscience
Research Sub Category
Oxidative Stress
This Anti-p67-phox Antibody is validated for use in IP, WB, IC for the detection of p67-phox.

Quality

routinely evaluated by immunoblot on RIPA lysates from HL-60 cells

Target description

65kDa

Physical form

Antiserum
rabbit antiserum containing 0.05% azide

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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INF-? Enhances Nox2 Activity by Upregulating phox Proteins When Applied to Differentiating PLB-985 Cells but Does Not Induce Nox2 Activity by Itself.
Ellison, MA; Thurman, G; Gearheart, CM; Seewald, RH; Porter, CC; Ambruso, DR
Testing null
Aswathy M Cheriyan et al.
American journal of physiology. Renal physiology, 320(5), F789-F798 (2021-02-23)
Calcineurin inhibitors (CNIs) are vital immunosuppressive therapies in the management of inflammatory conditions. A long-term consequence is nephrotoxicity. In the kidneys, the primary, catalytic calcineurin (CnA) isoforms are CnAα and CnAβ. Although the renal phenotype of CnAα-/- mice substantially mirrors
Katherine A Gauss et al.
Journal of leukocyte biology, 71(2), 319-328 (2002-01-31)
The NADPH oxidase plays an important role in immune and nonimmune cell functions. Because rabbits represent an established model for studying a number of important disease processes that involve NADPH oxidase activity, we carried out studies to clone and sequence
Aicha Bouraoui et al.
Free radical biology & medicine, 199, 113-125 (2023-02-25)
Poldip2 was shown to be involved in oxidative signaling to ensure certain biological functions. It was proposed that, in VSMC, by interaction with the Nox4-associated membrane protein p22phox, Poldip2 stimulates the level of reactive oxygen species (ROS) production. In vitro
D Roos et al.
Clinical and experimental immunology, 175(2), 139-149 (2013-09-11)
Patients with chronic granulomatous disease (CGD) suffer from recurrent, life-threatening bacterial and fungal infections of the skin, the airways, the lymph nodes, liver, brain and bones. Frequently found pathogens are Staphylococcus aureus, Aspergillus species, Klebsiella species, Burkholderia cepacia and Salmonella

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