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A59522

Sigma-Aldrich

2-Aminoindan hydrochloride

98%

Synonym(s):

2-Indanamine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C9H11N · HCl
CAS Number:
2338-18-3
Molecular Weight:
169.65
Beilstein:
3913700
EC Number:
219-048-0
MDL number:
MFCD00012549
UNSPSC Code:
12352100
PubChem Substance ID:
24891039
NACRES:
NA.22

Assay

98%

form

crystals

mp

245-247 °C (lit.)

SMILES string

Cl[H].NC1Cc2ccccc2C1

InChI

1S/C9H11N.ClH/c10-9-5-7-3-1-2-4-8(7)6-9;/h1-4,9H,5-6,10H2;1H

InChI key

XEHNLVMHWYPNEQ-UHFFFAOYSA-N

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Application

Prepared from 2-indanols via azide displacement and subsequent hydrogenation.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Loanda R Cumba et al.
The Analyst, 140(16), 5536-5545 (2015-06-24)
"Synthacaine" is a New Psychoactive Substance which is, due to its inherent psychoactive properties, reported to imitate the effects of cocaine and is therefore consequently branded as "legal cocaine". The only analytical approach reported to date for the sensing of
S X Ma et al.
The Journal of pharmacology and experimental therapeutics, 256(2), 751-756 (1991-02-01)
Dopaminergic structure-activity relationships of 2-aminoindans were evaluated for their ability to inhibit responses to stimulation of cardioaccelerator nerves in cats. The major observations were as follows: 1) Unsubstituted di-n-propyl- and diethyl 2-aminoindan derivatives do not inhibit responses to stimulation of
W Dimpfel et al.
BMC pharmacology, 11, 2-2 (2011-02-23)
Rasagiline, a new drug developed to treat Parkinson's disease, is known to inhibit monoamine oxidase B. However, its metabolite R-(-)-aminoindan does not show this kind of activity. The present series of in vitro experiments using the rat hippocampal slice preparation
S P Arnerić et al.
Archives internationales de pharmacodynamie et de therapie, 258(1), 84-99 (1982-07-01)
The ability of 2-aminotetralins (2-ATs), 2-aminoindanes (2-AIs), morphine (M) and clonidine (CLON) to alter neuroeffector transmission was studied on field-stimulated (FS) guinea-pig ilea (GPI). The activity of these compounds to inhibit K+, histamine (H), actylcholine (ACh), nicotine (Nic) and serotonin
H Wikström et al.
Journal of medicinal chemistry, 30(7), 1115-1120 (1987-07-01)
Conformational analyses on differently substituted 2-aminoindans of significant pharmacological interest were carried out by the molecular mechanics method (MM2). An X-ray structure of (R)-4-methoxy-2-aminoindan has shown the ammonium nitrogen [-)-D-tartaric acid salt) in an axial position. From comparison with other
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