404810
N,N′-Bis(3-aminopropyl)-1,3-propanediamine
technical grade, 90%
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About This Item
Linear Formula:
H2N(CH2)3NH(CH2)3NH(CH2)3NH2
CAS Number:
Molecular Weight:
188.31
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
grade
technical grade
Assay
90%
form
liquid
refractive index
n20/D 1.491 (lit.)
bp
98-103 °C/1 mmHg (lit.)
density
0.92 g/mL at 25 °C (lit.)
functional group
amine
SMILES string
NCCCNCCCNCCCN
InChI
1S/C9H24N4/c10-4-1-6-12-8-3-9-13-7-2-5-11/h12-13H,1-11H2
InChI key
ZAXCZCOUDLENMH-UHFFFAOYSA-N
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General description
N,N′-Bis(3-aminopropyl)-1,3-propanediamine, a linear polyamine, has been identified in white shrimp Penaeus setiferus by gas chromatography-mass spectrometry.
Application
N,N′-Bis(3-aminopropyl)-1,3-propanediamine (bappn) may be used in the preparation of [Ni(bappn)(ttcH)]·5H2O complex (ttch= trithiocyanurate dianion).
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point(F)
235.4 °F - closed cup
Flash Point(C)
113 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Protein kinase CK2 is a ubiquitous eukaryotic Ser/Thr kinase whose catalytic activity is enhanced several times by polyamines. We have shown previously that the regulatory beta-subunit of CK2 bears a polyamine binding site located in the region Asp51-Tyr110. In the
R H Hu et al.
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We have previously shown that simple N-acyl or N-alkyl polyamines bind to and sequester Gram-negative bacterial lipopolysaccharide, affording protection against lethality in animal models of endotoxicosis. Several iterative design-and-test cycles of SAR studies, including high-throughput screens, had converged on compounds
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