357847
2-Chloro-6-methylpyridine-3-carboxylic acid
97%
Synonym(s):
2-Chloro-6-methyl-3-pyridinecarboxylic acid, 2-Chloro-6-methylnicotinic acid
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About This Item
Empirical Formula (Hill Notation):
C7H6ClNO2
CAS Number:
Molecular Weight:
171.58
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Assay
97%
mp
162-164 °C (lit.)
SMILES string
Cc1ccc(C(O)=O)c(Cl)n1
InChI
1S/C7H6ClNO2/c1-4-2-3-5(7(10)11)6(8)9-4/h2-3H,1H3,(H,10,11)
InChI key
ACQXHCHKMFYDPM-UHFFFAOYSA-N
General description
2-Chloro-6-methylpyridine-3-carboxylic acid (2-Chloro-6-methylnicotinic acid) is a nicotinic acid derivative.
Application
2-Chloro-6-methylpyridine-3-carboxylic acid (2-Chloro-6-methylnicotinic acid) may be used in the synthesis of 6-methyl-2-thiophenoxynicotinic acid, required for the preparation of europium complex for staining the nucleolus of NIH 3T3, HeLa and HDF cells.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Junhua Yu et al.
Journal of the American Chemical Society, 128(7), 2294-2299 (2006-02-16)
A europium complex selectively staining the nucleolus of NIH 3T3, HeLa, and HDF cells is reported. This complex possesses not only the advantage of the long lifetime of europium emission (0.3 ms), but also a chromophore that allows excitation at
Nicotinic acid derivatives. VI. Some transformations of 2-chloro-6-methylnicotinic acid.
P Nantka-Namirski et al.
Polish journal of pharmacology and pharmacy, 26(5), 545-548 (1974-07-01)
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