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219746

Sigma-Aldrich

DL-Homocysteic acid

97%

Synonym(s):

DL-2-Amino-4-sulfobutyric acid

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About This Item

Linear Formula:
HO3SCH2CH2CH(NH2)CO2H
CAS Number:
504-33-6
Molecular Weight:
183.18
EC Number:
207-991-0
MDL number:
MFCD00007536
UNSPSC Code:
12352100
PubChem Substance ID:
24853141
NACRES:
NA.22

Assay

97%

form

solid

mp

273 °C (dec.) (lit.)

solubility

water: soluble 50 mg/mL, clear to slightly hazy, colorless to yellow

functional group

amine

SMILES string

NC(CCS(O)(=O)=O)C(O)=O

InChI

1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)

InChI key

VBOQYPQEPHKASR-UHFFFAOYSA-N

General description

Complexes of DL-homocysteic acid with Na+, Cu2+, Zn2+ and Ni2+ has been synthesized. DL-Homocysteic acid induces oxidative stress in brain of immature rats.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hui-Zhen Jia et al.
Guang pu xue yu guang pu fen xi = Guang pu, 27(7), 1291-1294 (2007-10-20)
The complexes of DL-homocysteic acid (DLH) with Na+, Cu2+, Zn2+ and Ni2+ were synthesized and elemental analyses were used to detect the compositions of these complexes. FTIR spectroscopy was employed to study these coordination structures. The results indicated that all
Jaroslava Folbergrová et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 31(2), 123-130 (2012-12-15)
We have recently demonstrated the evidence of oxidative stress in brain of immature rats during seizures induced by DL-homocysteic acid (DL-HCA). The aim of the present study was to investigate the antioxidant defense mechanisms under these conditions. Seizures were induced
Tohru Hasegawa et al.
PloS one, 5(1), e8593-e8593 (2010-01-26)
Alzheimer's disease (AD) is an age-associated progressive neurodegenerative disorder with dementia, the exact pathogenic mechanisms of which remain unknown. We previously reported that homocysteic acid (HA) may be one of the pathological biomarkers in the brain with AD and that
Peng Li et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 299(5), R1369-R1376 (2010-08-20)
We have shown that electroacupuncture (EA) inhibits sympathoexcitatory rostral ventrolateral medulla (rVLM) neurons and reflex responses following activation of a long-loop pathway in the arcuate nucleus and ventrolateral periaqueductal gray (vlPAG). Additionally, EA at P 5-6 acupoints (overlying the median
Marshall Bern et al.
Rapid communications in mass spectrometry : RCM, 24(6), 768-772 (2010-02-20)
Analysis of protein oxidation is necessary in numerous areas of biochemistry, including hydroxyl radical surface mapping, oxidative stress assays, and pharmaceutical stability testing. Mass spectrometry is one of the tools most often used to identify protein oxidation products, and previous
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