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217808

Sigma-Aldrich

cis-Aconitic anhydride

95%

Synonym(s):

cis-Propene-1,2,3-tricarboxylic anhydride

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About This Item

Empirical Formula (Hill Notation):
C6H4O5
CAS Number:
6318-55-4
Molecular Weight:
156.09
Beilstein:
127575
EC Number:
228-663-3
MDL number:
MFCD00005524
UNSPSC Code:
12162002
PubChem Substance ID:
24853034
NACRES:
NA.23

Assay

95%

mp

75-78 °C (lit.)

SMILES string

OC(=O)CC1=CC(=O)OC1=O

InChI

1S/C6H4O5/c7-4(8)1-3-2-5(9)11-6(3)10/h2H,1H2,(H,7,8)

InChI key

GVJRTUUUJYMTNQ-UHFFFAOYSA-N

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Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Abhijeet Pandey et al.
Materials science & engineering. C, Materials for biological applications, 98, 419-436 (2019-03-01)
In the present investigation, FePt alloy nanoparticles were synthesized with controlled size and elemental composition followed by surface modification using (3-Aminopropyl) triethoxysilane (APTES). Lenalidomide was covalently bound to FePt-NH2 by pH sensitive hydrazone bonding. Hyaluronic acid was conjugated to amino
Peng-Fei Cui et al.
Journal of controlled release : official journal of the Controlled Release Society, 303, 253-262 (2019-04-28)
Cationic polymeric vectors attracted plenty of attentions in gene therapy due to nonimmunogenicity, easy to synthesis and flexible properties. However, biocompatibility challenge such as nonspecific interactions with blood cells and serum proteins, may affect the delivery efficiency of cationic vectors;
J A Kamps et al.
Biochimica et biophysica acta, 1278(2), 183-190 (1996-01-31)
Human serum albumin (HSA) derivatized with cis-aconitic anhydride (Aco-HSA) that was earlier shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1), was covalently coupled to conventional liposomes, consisting of phosphatidylcholine, cholesterol and maleimido-4-(p-phenylbutyryl)phosphatidylethanolamine, using the heterobifunctional reagent N-succinimidyl-S-acetylthioacetate
M Wirth et al.
Pharmaceutical research, 15(7), 1031-1037 (1998-08-04)
To investigate the usefulness of wheat germ agglutinin as a targeting carrier protein for an acid-labile chemotherapeutic prodrug directed against colon carcinoma cells in vitro. Cis-aconityl-linked doxorubicin-wheat germ agglutinin was prepared by a two step procedure and the conjugate-binding capacity
Ming Zhao et al.
Natural product communications, 7(6), 785-787 (2012-07-24)
From the seeds of Alisma orientale, cis-aconitic anhydride ethyl ester and cis-2,4,5-trihydroxycinnamic acid were isolated, together with nine known phenolic compounds and a megastigmane sesquiterpene. All compounds are reported for the first time from Alisma species.
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