MLS0001
MISSION® LightSwitch Luciferase Assay Reagent™
Fully optimized reporter system
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About This Item
UNSPSC Code:
41106609
NACRES:
NA.84
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General description
The MISSION LightSwitch Luciferase Assay Reagent enables one-step reagent addition to measure luciferase reporter signal. The MISSION LightSwitch Luciferase Assay Reagent and the MISSION 3′UTR Lenti GoClone report constructs are a fully optimized reporter system that includes an improved reporter gene (RenSP), an optimized assay reagent, and a genome-wide collection of 3′UTR Lenti GoClone reporter constructs. The MISSION 3′UTR Lenti GoClone reporter constructs have been optimized for use with the MISSION LightSwitch Assay Reagent.
Application
MISSION® LightSwitch Luciferase Assay Reagent™ has been used to measure actin promoter activity.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
SwitchGear Genomics is a trademark of SwitchGear Genomics
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Storage Class Code
3 - Flammable liquids
Flash Point(F)
51.8 °F
Flash Point(C)
11 °C
Certificates of Analysis (COA)
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An NTD-associated polymorphism in the 3' UTR of MTHFD1L can affect disease risk by altering miRNA binding.
Minguzzi S
Human Mutation, 35(1), 96-104 (2014)
The PLA2R1-JAK2 pathway upregulates ERRa and its mitochondrial program to exert tumor-suppressive action.
Griveau A
Oncogene, 35(38), 5033-5042 (2016)
Nathan D Trinklein et al.
Genome research, 14(1), 62-66 (2004-01-07)
The alignment of full-length human cDNA sequences to the finished sequence of the human genome provides a unique opportunity to study the distribution of genes throughout the genome. By analyzing the distances between 23,752 genes, we identified a class of
Pieter Mestdagh et al.
Molecular cell, 40(5), 762-773 (2010-12-15)
The miR-17-92 microRNA cluster is often activated in cancer cells, but the identity of its targets remains elusive. Using SILAC and quantitative mass spectrometry, we examined the effects of activation of the miR-17-92 cluster on global protein expression in neuroblastoma
Janosch Hildebrand et al.
The Journal of investigative dermatology, 131(1), 20-29 (2010-09-10)
Here, we report a comprehensive investigation of changes in microRNA (miRNA) expression profiles on human keratinocyte (HK) differentiation in vitro and in vivo. We have monitored expression patterns of 377 miRNAs during calcium-induced differentiation of primary HKs, and have compared
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