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Key Documents

Y0001521

Amoxicillin trihydrate for performance verification

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Amoxicillin trihydrate

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About This Item

Empirical Formula (Hill Notation):
C16H19N3O5S · 3H2O
CAS Number:
Molecular Weight:
419.45
Beilstein:
7507120
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

amoxicillin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(O)=O

InChI

1S/C16H19N3O5S.3H2O/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7;;;/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24);3*1H2/t9-,10-,11+,14-;;;/m1.../s1

InChI key

MQXQVCLAUDMCEF-CWLIKTDRSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Amoxicillin trihydrate for performance verification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Description
Pricing

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Development and Validation of RP-HPLC Method for Simultaneous Estimation of Amoxicillin trihydrate and Flucloxacillin sodium in capsule dosage form.
Nikam.S D, et al.
International Journal of PharmTech Research, 1(3), 935-939 (2009)
In acute calculous cholecystitis, antibiotics after cholecystectomy did not reduce infection.
Daniel I Steinberg
Annals of internal medicine, 161(12), JC4-JC4 (2014-12-17)
Ambrose Agweyu et al.
Tropical medicine & international health : TM & IH, 19(11), 1310-1320 (2014-08-19)
To determine the extent and pattern of treatment failure (TF) among children hospitalised with community-acquired pneumonia at a large tertiary hospital in Kenya. We followed up children aged 2-59 months with WHO-defined severe pneumonia (SP) and very severe pneumonia (VSP)
Salomone Di Saverio et al.
Annals of surgery, 260(1), 109-117 (2014-03-22)
To assess the safety and efficacy of antibiotics treatment for suspected acute uncomplicated appendicitis and to monitor the long term follow-up of non-operated patients. Right lower quadrant abdominal pain is a common cause of emergency department admission. The natural history
Clinical trial evidence to advance the science of cholecystectomy.
Joseph S Solomkin
JAMA, 312(2), 135-136 (2014-07-10)

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