Skip to Content
Merck
All Photos(1)

Documents

72420

Sigma-Aldrich

Methyl nicotinate

puriss., ≥99.0% (GC)

Synonym(s):

Nicotinic acid methyl ester

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C7H7NO2
CAS Number:
Molecular Weight:
137.14
Beilstein:
113951
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

biological source

synthetic

Quality Level

grade

puriss.

Assay

≥99.0% (GC)

form

powder or crystals (possibly with chunks)

color

white to faint yellow

bp

204 °C (lit.)

mp

39-42 °C
42-44 °C (lit.)

solubility

H2O: 0.1 g/mL, clear

SMILES string

COC(=O)c1cccnc1

InChI

1S/C7H7NO2/c1-10-7(9)6-3-2-4-8-5-6/h2-5H,1H3

InChI key

YNBADRVTZLEFNH-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Methyl nicotinate (or nicotinic acid methyl ester) is used as a rubefacient for the relief of pains in muscles, tendons, and joints. It is also used in food as a flavoring agent.

Application

Methyl nicotinate can be used as a precursor:
  • In the asymmetric synthesis of 1-azasugars (glycosidase inhibitors) for biomedical applications.
  • In the total synthesis of ±-sesbanine.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

Topical antirheumatic agents as hydroxyl radical scavengers
Billany MR, et al.
International Journal of Pharmaceutics, 124(2), 279-283 (1995)
A facile synthesis of ? -sesbanine via γ-addition of ketene silyl acetal with quaternized methyl nicotinate
Wada M, et al.
Tetrahedron Letters, 26(27), 3267-3270 (1985)
Selective fowler reductions: asymmetric total syntheses of isofagomine and other 1-azasugars from methyl nicotinate
Zhao G, et al.
Organic Letters, 3(2), 201-203 (2001)
Jim O'Doherty et al.
Journal of biomedical optics, 14(3), 034025-034025 (2009-07-02)
The use of laser Doppler perfusion imaging (LDPI) and laser speckle perfusion imaging (LSPI) is well known in the noninvasive investigation of microcirculatory blood flow. This work compares the two techniques with the recently developed tissue viability (TiVi) imaging system
Melissa Kerr et al.
Prostaglandins, leukotrienes, and essential fatty acids, 79(1-2), 15-19 (2008-07-29)
Topical application of nicotinic acid results in erythema, and in some cases oedema of the skin, supporting a strong relationship between niacin sensitivity and prostaglandin D2. The aim of this study was to examine the inter-rater and intra-rater reliability of

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service