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56805

Supelco

Ginsenoside Rh1

analytical standard

Synonym(s):

(3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl-β-D-glucopyranoside, Prosapogenin A2, Sanchinoside B2, Sanchinoside Rh1

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About This Item

Empirical Formula (Hill Notation):
C36H62O9
CAS Number:
Molecular Weight:
638.87
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥90.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

C\C(C)=C/CC[C@](C)(O)[C@H]1CC[C@]2(C)[C@@H]1[C@H](O)C[C@@H]3[C@@]4(C)CC[C@H](O)C(C)(C)[C@@H]4[C@H](C[C@@]23C)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O

InChI

1S/C36H62O9/c1-19(2)10-9-13-36(8,43)20-11-15-34(6)26(20)21(38)16-24-33(5)14-12-25(39)32(3,4)30(33)22(17-35(24,34)7)44-31-29(42)28(41)27(40)23(18-37)45-31/h10,20-31,37-43H,9,11-18H2,1-8H3/t20-,21+,22-,23+,24+,25-,26-,27+,28-,29+,30-,31+,33+,34+,35+,36-/m0/s1

InChI key

RAQNTCRNSXYLAH-RFCGZQMISA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: panax

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Yusheng Gai et al.
Toxicology mechanisms and methods, 22(8), 584-591 (2012-06-15)
The present study was designed to investigate the effect of ginsenoside Rh1 on myocardial injury and heart function in isoproterenol-induced cardiotoxicity in rats. Sprague-Dawley rats were subcutaneously injected with isoproterenol (20 mg/kg). Cardiac marker enzymes in serum, antioxidative parameters and
Wan Gu et al.
Biological & pharmaceutical bulletin, 36(1), 102-107 (2013-01-11)
Ginseng (the root of Panax ginseng C. A. MEYER), which contains protopanaxadiols and protopanaxatriols as its main constituents, has been used for many disorders, such as cancer, diabetes, inflammation, and hyperlipidemia. Of these ginsenosides, protopanaxadiol ginsenoside Rh2 alone is reported
Yeo-Jin Choi et al.
Fitoterapia, 82(6), 911-919 (2011-05-25)
Ginsenoside Rh1 has been reported to possess antiallergic and anti-inflammatory activities, but its effects on monocytes remain to be determined. Herein, we investigated the effects of Rh1 on the expression of MCP-1 and CCR2, activation of MAPK signaling, and chemotaxis
Ji-Sun Jung et al.
Biochemical and biophysical research communications, 397(2), 323-328 (2010-06-01)
Microglial activation plays an important role in the pathogenesis of various neurodegenerative diseases by producing neurotoxic factors, such as pro-inflammatory cytokines and nitric oxide (NO). In the present study, we found that protopanaxatriol ginsenoside Rh1 suppresses NO, ROS, and TNF-alpha
Jingang Hou et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 34(23), 3030-3033 (2010-03-13)
To obtain 20(S)-ginsenoside Rh1 by the method of enzymolysis with the protopananxtriol saponins, and to provide the theory for large-scale preparation of 20(S)-ginsenoside Rh1. AB-8 macroporous resin was used to isolate the total saponins of the stems and leaves from

Articles

In this article we present several HPTLC applications and analytical standards for ginsenosides.

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