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Supelco

Fenbendazole

VETRANAL®, analytical standard

Synonym(s):

Methyl 5-(phenylthio)-2-benzimidazolecarbamate

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About This Item

Empirical Formula (Hill Notation):
C15H13N3O2S
CAS Number:
43210-67-9
Molecular Weight:
299.35
Beilstein:
759077
EC Number:
256-145-7
MDL number:
MFCD00144301
UNSPSC Code:
41116107
PubChem Substance ID:
329755115
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

COC(=O)Nc1nc2cc(Sc3ccccc3)ccc2[nH]1

InChI

1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)

InChI key

HDDSHPAODJUKPD-UHFFFAOYSA-N

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General description

Chemical structure: benzimidazole
Fenbendazole is a thio substituted benzimidazole, which belongs to the group of anthelmintics. It can be widely used in veterinary medicine particularly, in the treatment of helminth infections.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Product No.
Description
Pricing

Pictograms

Health hazardEnvironment
GHS08,GHS09

Signal Word

Warning

Hazard Statements

H361fd,H373,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2

Target Organs

Liver,lymph node,Stomach,Nervous system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK6626
BCBZ7464
BCBS1202V
SZBF223XV
SZBB325XV

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Determination of fenbendazole and oxfendazole in liver and muscle using liquid chromatography?mass spectrometry
Blanchflower J.W, et al.
Analyst, 119, 1325-1328 (1994)
Interaction between fenbendazole and piperonyl butoxide: pharmacokinetic and pharmacodynamic implications
Benchaoui.A.H and Mckellar.A.Q
The Journal of Pharmacy and Pharmacology, 48, 753-759 (1996)
Walter Boyce et al.
Veterinary parasitology, 180(3-4), 256-261 (2011-04-19)
Canine peritoneal larval cestodiasis (CPLC) is a poorly understood disease of dogs caused by asexual multiplication of larval Mesocestoides spp. tapeworms. In this study, we examined the descriptive statistics and survival characteristics of 60 dogs diagnosed with CPLC from 1989
Unexpected production loss caused by helminth parasites in weaned beef calves.
N D Sargison et al.
The Veterinary record, 167(19), 752-754 (2011-01-25)
C Chassaing et al.
Journal of medicinal chemistry, 51(5), 1111-1114 (2008-02-15)
Highly water-soluble prodrugs 1a- g of anthelmintic benzimidazole carbamates 2a- g were synthesized. These prodrugs combine high aqueous solubility and stability with high lability in the presence of alkaline phosphatases. The veterinary utility of 1a was shown by a pharmacodynamic
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