1.04350

L-Histidine monohydrochloride monohydrate

for biochemistry

• Synonym(s): His, L-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride
• Empirical Formula (Hill Notation): C₆H₉N₃O₂ · HCl · H₂O
• CAS Number: 5934-29-2
• Molecular Weight: 209.63
• Beilstein: 4168261
• MDL number: MFCD00151027
• UNSPSC Code: 12352209
• EC Index Number: 211-438-9
• NACRES: NA.21

Properties

• vapor pressure: <1 hPa ( 20 °C)
• Quality Level: 100
• form: crystalline powder
• pH: 3.5-4.5 (20 °C, 100 g/L in H₂O)
• mp: 254 °C (dec.) (lit.)
• solubility: 149.55 g/L
• density: 1.49 g/cm³ at 20 °C
• bulk density: 770 kg/m³
• storage temp.: 2-30°C
• SMILES string: O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
• InChI: 1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
• InChI key: CMXXUDSWGMGYLZ-XRIGFGBMSA-N

Description

Analysis Note

Assay (alkalimetric, calculated on dried substance): ≥ 99.0 %
Identity (IR-spectrum): passes test
Appearance: white to almost white crystalline powder or colorless crystals
Appearance of solution (50 g/l CO₂-free water): clear and colorless
Spec. rotation (α 20/D, 110 g/l, hydrochloric acid 120 g/l, calc. on dried substance): +9.2 to +10.6
Sulfate (SO₄): ≤ 0.02 %
Heavy metals (as Pb): ≤ 0.001 %
As (Arsenic): ≤ 0.0005 %
Ca (Calcium): ≤ 0.001 %
Co (Cobalt): ≤ 0.0005 %
Fe (Iron): ≤ 0.0005 %
K (Potassium): ≤ 0.0005 %
Mg (Magnesium): ≤ 0.0005 %
Na (Sodium): ≤ 0.005 %
NH₄ (Ammonium): ≤ 0.01 %
Zn (Zinc): ≤ 0.0005 %
Foreign amino acids: ≤ 0.3 %
Other ninhydrine positive substances: ≤ 0.1 %
Loss on drying (150 °C): 7.0 - 10.0 %

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable