Skip to Content
Merck
All Photos(1)

Documents

439533

Sigma-Aldrich

2,4,6-Tribromo-3-hydroxybenzoic acid

97%

Synonym(s):

3-Hydroxy-2,4,6-tribromobenzoic acid

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
HC6Br3(OH)CO2H
CAS Number:
Molecular Weight:
374.81
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

powder

mp

145-148 °C (lit.)

SMILES string

OC(=O)c1c(Br)cc(Br)c(O)c1Br

InChI

1S/C7H3Br3O3/c8-2-1-3(9)6(11)5(10)4(2)7(12)13/h1,11H,(H,12,13)

InChI key

YDBHVMTTYXWHLI-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

2,4,6-Tribromo-3-hydroxybenzoicacid (TBHBA) is an organic compound used as a building block. TBHBA is an enzymic colorimetric reagent to determine the free cholesterol fraction of high-density lipoprotein (HDL) in plasma.

Application


  • One-pot synthesis and nano-bio applications: Research described a one-pot bottom-up synthesis technique for a 2D graphene derivative, utilizing 2,4,6-Tribromo-3-hydroxybenzoic acid, demonstrating its applications in biomolecular recognition and nanozyme activities (Pandit and De, 2021).

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

J S Moshides
Scandinavian journal of clinical and laboratory investigation, 48(1), 59-64 (1988-02-01)
A sensitive enzymatic method for the measurement of high density lipoprotein choline-containing phospholipids (HDL-pc) was adapted to a Cobas Bio Centrifugal Analyzer. The Boehringer Mannheim phospholipase D/choline oxidase/peroxidase reagent was modified by the inclusion of 2,4,6,-tribromo-3-hydroxybenzoic acid (TBHBA) which reacts
P Trinder et al.
Annals of clinical biochemistry, 21 ( Pt 5), 430-433 (1984-09-01)
The Boehringer one-component high-performance cholesterol oxidase reagent has been modified by the inclusion of 2,4,6-tribromo-3-hydroxybenzoic acid (TBHBA) to give a fourfold increase in sensitivity to a molar absorbance of approximately equal to 29,000 with respect to cholesterol. The resulting reagent
One-pot bottom-up synthesis of a 2D graphene derivative: Application in biomolecular recognition and nanozyme activity
Pandit S, et al.
Nanoscale advances, 3(17), 5102-5110 (2021)
J S Moshides
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 25(9), 583-587 (1987-09-01)
A sensitive fixed-time kinetic enzymatic method for the measurement of high density lipoprotein cholesterol is described, as adapted for the Cobas Bio centrifugal analyser (Hoffmann LaRoche). The Boehringer Mannheim cholesterol esterase/cholesterol oxidase/peroxidase/3,4-dichlorophenol kinetic reagent was modified by the inclusion of
Sandra Abad et al.
Microbial cell factories, 9, 24-24 (2010-04-28)
Trigonopsis variabilis D-amino acid oxidase (TvDAO) is a well characterized enzyme used for cephalosporin C conversion on industrial scale. However, the demands on the enzyme with respect to activity, operational stability and costs also vary with the field of application.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service