推荐产品
等級
pharmaceutical primary standard
API 家族
torsemide
製造商／商標名
USP
應用
pharmaceutical (small molecule)
格式
neat
SMILES 字串
CC(C)NC(=O)NS(=O)(=O)c1cnccc1Nc2cccc(C)c2
InChI
1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)
InChI 密鑰
NGBFQHCMQULJNZ-UHFFFAOYSA-N
基因資訊
human ... SLC12A1(6557)
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一般說明
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
應用
Torsemide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
Also, for use with USP monographs such as:
- Torsemide Tablets
- Torsemide Compounded Oral Suspension
生化／生理作用
Torsemide is a loop diuretic of the pyridine-sulfonylurea class with antialdosteronergic properties and inhibitor of the Na+/K+/2Cl- carrier system.
分析報告
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他說明
Sales restrictions may apply.
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Repr. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
James J DiNicolantonio
Future cardiology, 8(5), 707-728 (2012-09-28)
Furosemide is the most widely prescribed loop diuretic in the setting of systolic heart failure (HF), yet torsemide has been shown to have less inter- and intra-individual variation in bioavailability and a longer duration of action compared with furosemide. Thus
S F Fowler et al.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 52(16), 1771-1780 (1995-08-15)
The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and dosage and administration of torsemide are reviewed. Torsemide belongs to the pyridine-sulfonylurea class of loop diuretics. Its primary site of activity is the thick ascending limb of the loop of Henle, where
J S Blose et al.
The Annals of pharmacotherapy, 29(4), 396-402 (1995-04-01)
To review the clinical pharmacology of torsemide and to compare it with currently available loop diuretics, particularly furosemide. An English-language MEDLINE search, 1985 to October 1994, was used to identify pertinent literature, including review articles. Data from scientific literature were
Loop diuretics: comparison of torsemide, furosemide, and bumetanide.
B P Chen
Connecticut medicine, 60(6), 343-345 (1996-06-01)
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