1356971

来曲唑

United States Pharmacopeia (USP) Reference Standard

• 别名: 4,4′-(1H-1,2,4-三唑-1-基亚甲基）双苄腈
• 经验公式（希尔记法）: C₁₇H₁₁N₅
• CAS号: 112809-51-5
• 分子量: 285.30
• MDL號碼: MFCD00866241
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329750236
• NACRES: NA.24

属性

• 等級: pharmaceutical primary standard
• API 家族: letrozole
• 製造商／商標名: USP
• 應用: pharmaceutical (small molecule)
• 格式: neat
• SMILES 字串: N#CC(C=C1)=CC=C1C(N2C=NC=N2)C3=CC=C(C#N)C=C3
• InChI: 1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
• InChI 密鑰: HPJKCIUCZWXJDR-UHFFFAOYSA-N
• 基因資訊: human ... CYP19A1(1588)

说明

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Letrozole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Letrozole Tablets

生化／生理作用

来曲唑是第三代非甾体芳香酶抑制剂。 它是芳香酶系统的竞争性抑制剂，因此可抑制雄激素向雌激素转化。来曲唑通过竞争性结合到该酶的细胞色素P450亚基的血红素上而抑制芳香酶，导致所有组织中雌激素的生物合成减少。

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

安全信息

• 象形圖: GHS08
• 訊號詞: Warning
• 危險聲明: H361fd,H373
• 防範說明: P202 - P260 - P280 - P308 + P313 - P405 - P501
• 危險分類: Repr. 2 - STOT RE 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable