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Merck

1269200

USP

法莫替丁

United States Pharmacopeia (USP) Reference Standard

别名:

N′-(氨基磺酰基)-3-([2-(二氨基亚甲基氨基)-4-噻唑基]甲硫基)丙脒

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About This Item

经验公式(希尔记法):
C8H15N7O2S3
CAS号:
分子量:
337.45
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

生物源

synthetic

等級

pharmaceutical primary standard

agency

USP

蒸汽壓力

<0.0000001 kPa ( 25 °C)

API 家族

famotidine

形狀

powder

包裝

pkg of 125 mg

製造商/商標名

USP

儲存條件

protect from light

顏色

white to pale yellow-white

mp

325.4-327.2 °F (163—164°C)

溶解度

DMF: freely soluble
acetone: practically insoluble
chloroform: practically insoluble
ethanol: practically insoluble
ether: practically insoluble
ethyl acetate: practically insoluble
glacial acetic acid: freely soluble
methanol: slightly soluble
water: very slightly soluble

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1

InChI

1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)

InChI 密鑰

XUFQPHANEAPEMJ-UHFFFAOYSA-N

基因資訊

human ... HRH2(3274)

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一般說明

Famotidine is a hydrophilic, cationic, histamine H2 receptor antagonist drug that effectively inhibits gastric acid secretion in humans.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Famotidine can be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by various analytical techniques.(10)

生化/生理作用

H2组胺受体拮抗剂;抗溃疡剂。

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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其他客户在看

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Simultaneous determination of famotidine and flurbiprofen by high performance liquid chromatography
Hanif M, et al.
Tropical Journal of Pharmaceutical Research, 15(3), 605-611 (2016)
Determination of famotidine in acid reduction tablets by HPTLC and videodensitometry of fluorescence quenched zones
Campbell AN and Sherma J
Journal of Liquid Chromatography and Related Technologies, 26(16), 2719-2727 (2003)
Determination of cimetidine, famotidine, and ranitidine hydrochloride in the presence of their sulfoxide derivatives in pure and dosage forms by high-performance thin-layer chromatography and scanning densitometry
Kelani KM, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 85(5), 1015-1020 (2002)
Stability indicating method for famotidine in pharmaceuticals using porous graphitic carbon column
Helali N and Monser L
Journal of Separation Science, 31(2) (2008)
Development and validation of chromatographic methods for simultaneous determination of ibuprofen and famotidine in presence of related substances in pharmaceutical formulations
Elzanfaly ES, et al.
Acta Chimica Slovenica, 62(1) (2014)

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