推荐产品
等級
pharmaceutical primary standard
API 家族
abacavir
製造商／商標名
USP
應用
pharmaceutical (small molecule)
格式
neat
儲存溫度
2-8°C
InChI
1S/C11H14N6O/c12-9-8-10(16-11(13)15-9)17(5-14-8)7-2-1-6(3-7)4-18/h1-2,5-7,18H,3-4H2,(H4,12,13,15,16)/t6-,7+/m1/s1
InChI 密鑰
ZKJUXHDSLJYKED-RQJHMYQMSA-N
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一般說明
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
應用
Abacavir Related Compound A USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
分析報告
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他說明
Sales restrictions may apply.
相關產品
产品编号
说明
价格
訊號詞
Danger
危險聲明
危險分類
Eye Dam. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Y Wen et al.
Drug metabolism and disposition: the biological fate of chemicals, 27(1), 113-121 (1999-01-12)
Several in vitro and in situ approaches were used to determine the dominant presystemic activation site for (-)-6-aminocarbovir, (-)-carbocyclic 2',3'-didehydro-2', 3'-dideoxy-6-deoxy-6-aminoguanosine (6AC) conversion in rats. The in vitro disappearance half-lives (mean +/- S.D.) in the cytosolic fractions obtained from homogenates
C L Zimmerman et al.
Drug metabolism and disposition: the biological fate of chemicals, 20(1), 47-51 (1992-01-01)
The recently synthesized carbocyclic 2',3'-didehydro-2',3'-dideoxy-6-deoxy-6-amino-guanosine [(-)6AC] was evaluated as a prodrug for carbovir, carbocyclic 2',3'-didehydro-2',3'-dideoxyguanosine [(-)CBV] in seven male Sprague-Dawley rats. A randomized three-way cross-over design was used. Rats were assigned to receive the following treatments: a 20 mg/kg (-)6AC
Lack of effect of catheterization on the pharmacokinetics of (-)-carbovir in rats.
C L Zimmerman et al.
Pharmaceutical research, 13(9), 1417-1418 (1996-09-01)
Evaluation of gastrointestinal absorption and metabolism.
C L Zimmerman et al.
Drug metabolism reviews, 29(4), 957-975 (1998-01-09)
Y D Wen et al.
Pharmaceutical research, 12(6), 911-915 (1995-06-01)
Evaluate the ability of (-)-6-aminocarbovir ((-)-6AC) to improve the CNS exposure to (-)-carbovir ((-)-CBV). Activation of (-)-6AC in vitro was assessed by incubations of rat brain tissue homogenates. The in vivo brain exposure to (-)-CBV was then examined in rats
相关内容
Small molecules are ions and compounds of molecular weight typically less than 900 daltons. These compounds can be effectively separated and analyzed by HPLC, UHPLC and LC-MS using mainly silica particles or monolithic stationary phases with a broad range of column chemistries (modifications).
小分子为离子和化合物，分子量通常低于900道尔顿。这类化合物可使用柱化学性质各异的硅胶颗粒型或整体型固定相，通过HPLC、UHPLC和LC-MS等方法有效分离和分析。
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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