技術
HPLC: suitable
測試參數
column: Astec Cellulose DMP; 25 cm x 4.6 mm I.D., 5 μm particles (51099AST)
mobile phase: [A] heptane; [B] isopropanol; (80:20, A:B)
flow rate: 1 mL/min
column temp.: 30 °C
detector: UV, 254 nm
injection: 15 μL
sample: mephobarbital, 1 g/L in 50:50, heptane:isopropanol
適合性
application for HPLC
應用
pharmaceutical (small molecule)
分析報告
Mephobarbital enantiomers are resolved by normal phase chromatography.
其他說明
Mephobarbital (aka methyphenobarbital) is used as a sedative, anxiolytic and anticonvulsant. It is the N-methylated analogue of phenobarbital, and has similiar indications, therapeutic value, and tolerability.
法律資訊
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
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