推荐产品
product name
SUPELCOSIL ™ LC-ABZ HPLC 色谱柱, 5 μm particle size, L × I.D. 25 cm × 3 mm
材料
stainless steel column
agency
suitable for USP L60
產品線
SUPELCOSIL™
特點
endcapped
製造商/商標名
SUPELCOSIL™
包裝
1 ea of
標籤範圍
12.0% carbon loading
參數
≤70 °C temp. limit
400 bar pressure (5801 psi)
技術
HPLC: suitable
長度 × 內徑
25 cm × 3 mm
表面積
170 m2/g
表面覆盖率
surface coverage 3.4 μmol/m2
基質
silica gel, spherical particle platform
fully porous particle
基質活性組
amide, alkyl phase
粒徑
5 μm
孔徑
120 Å
pH值範圍
2-7.5
應用
food and beverages
分離技術
reversed phase
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相关类别
一般說明
SUPELCOSIL LC-ABZ 相具有独特的去活技术,该可为碱性化合物以及酸性、中性和非极性化合物提供出色的反相性能。不需要采取使用同类胺在高离子强度下运行,以及调节流动相的极端 pH 值来抑制硅烷醇活性,就可以在 LC-ABZ 相上获得良好的峰形。
特點和優勢
• 用于酸性、碱性、两性离子
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物,峰形、柱效和保留性相当于 C8 相
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物,峰形、柱效和保留性相当于 C8 相
法律資訊
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Pharmacy world & science : PWS, 20(2), 83-87 (1998-05-19)
To study the pharmacokinetics of dextromoramide in long-term opiate addicts on methadone maintenance therapy (MMT) a reverse-phase HPLC technique was developed to monitor dextromoramide and methadone concentrations in plasma simultaneously. After liquid-liquid extraction from plasma, dextromoramide and methadone were determined
The Analyst, 128(5), 427-433 (2003-06-07)
The solvation parameter model is used to identify suitable chromatographic models for estimating the octanol-water partition coefficient for neutral compounds of varied structure by reversed-phase liquid chromatography. The stationary phase Supelcosil LC-ABZ with methanol-water mobile phases affords a series of
Journal of chromatography. A, 870(1-2), 105-114 (2000-03-18)
A high-performance liquid chromatographic method with electrochemical detection has been developed for the determination of six 1,4-dihydropyridines: nifedipine, nimodipine, nisoldipine, nicardipine, felodipine and lacidipine. The chromatographic separation was performed using a Supelcosil LC-ABZ+Plus C18 column. A mobile phase of methanol-water
Journal of separation science, 32(20), 3418-3424 (2009-09-19)
Streptomycin (SM) is composed of streptidine, streptose and N-methyl glucosamine sugar moieties. For the determination of SM and its related substances, an ion-pair LC-UV detection method using a Supelcosil LC-ABZ column was developed previously. While analyzing commercial samples, several unknown
Journal of chromatographic science, 38(6), 246-254 (2000-07-13)
Nevirapine (Viramune), a dipyridiodiazepinone, is a potent and highly specific nonnucleoside inhibitor of HIV-1 reverse transcriptase. This paper describes the validation of a specific, sensitive, and stability-indicating high-performance liquid chromatography method for the assay and determination of related organic impurities
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