569253-U

Discovery^® HS C18 (3 µm) HPLC Columns

L × I.D. 5 cm × 2.1 mm, HPLC Column

• 别名: Discovery RP18 HPLC Column
• 分類程式碼代碼: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

属性

• product name: Discovery^® HS C18 高效液相色谱柱, 3 μm particle size, L × I.D. 5 cm × 2.1 mm
• 材料: stainless steel column
• agency: suitable for USP L1
• 產品線: Discovery^®
• 特點: endcapped
• 製造商／商標名: Discovery^®
• 包裝: 1 ea of
• 標籤範圍: 20% Carbon loading
• 參數: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• 技術: HPLC: suitable; LC/MS: suitable
• 長度 × 內徑: 5 cm × 2.1 mm
• 表面積: 300 m²/g
• 表面覆盖率: 3.2 μmol/m²
• 雜質: <10 ppm metals
• 基質: silica gel, high purity, spherical particle platform; fully porous particle
• 基質活性組: C18 (octadecyl) phase
• 粒徑: 3 μm
• 孔徑: 120 Å
• 工作pH值範圍: 2-8
• 應用: food and beverages
• 分離技術: reversed phase

说明

一般說明

Discovery^® HS C18 HPLC column (L × I.D. 5 cm × 2.1 mm) is commonly found to be stable under acidic and basic conditions.

應用

• Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping: This research utilizes the Discovery^® HS C18 HPLC column for its superior selectivity and sensitivity in pharmacogenetic studies, providing vital data for personalized medicine approaches in drug metabolism (Abouir et al., 2024).


• A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies: This study highlights the effectiveness of the Discovery^® HS C18 column in the rapid and accurate analysis of molnupiravir, emphasizing its role in supporting fast-paced pharmaceutical research and development (Reçber et al., 2022).


• Sensitive Analysis of Idarubicin in Human Urine and Plasma by Liquid Chromatography with Fluorescence Detection: This application underlines the Discovery^® HS C18 column′s high sensitivity and robustness in clinical diagnostics, crucial for monitoring therapeutic drugs and their metabolites in complex biological matrices (Maliszewska et al., 2020).

特點和優勢

• 稳定性好、低流失，适用于 LC-MS 分析
• 提供有适用于分析型到制备型的各种规格
• 稳定性好，以确保柱与柱和批与批之间之间优良的重现性
• 更强的疏水性能够更好地分离难分析化合物

   

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法律資訊

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany