所有图片(1)
About This Item
经验公式（希尔记法）:
C26H20N2O
CAS号:
分子量:
376.45
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
推荐产品
产品名称
XE-991, ≥98% (HPLC)
方案
≥98% (HPLC)
颜色
white to beige
溶解性
DMSO: >20 mg/mL
创始人
Merck & Co., Inc., Kenilworth, NJ, U.S.
储存温度
2-8°C
SMILES字符串
O=C1c2ccccc2C(Cc3ccncc3)(Cc4ccncc4)c5ccccc15
InChI
1S/C26H20N2O/c29-25-21-5-1-3-7-23(21)26(17-19-9-13-27-14-10-19,18-20-11-15-28-16-12-20)24-8-4-2-6-22(24)25/h1-16H,17-18H2
InChI key
KHJFBUUFMUBONL-UHFFFAOYSA-N
应用
XE-991已被利用KCNQ（Kv7.2 / 7.3）抑制剂，以检查M电流抑制是否影响催产素受体（TGOT）介导的去极化。也曾作为 KCNQ 抑制剂用于研究河豚毒素（TTX）存在时小鼠胆碱能中间神经元（ChIs）膜电位超射/欠射的离子机制。
生化/生理作用
XE-991 是一种 KCNQ 通道阻滞剂。
XE-991 是一种 KCNQ 通道阻滞剂；它比利诺哌啶（目录号L-134）更有效。
特点和优势
该化合物是由Merck & Co., Inc., Kenilworth, NJ, U.S.开发的。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单，请单击此处。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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