WH0004653M1

Monoclonal Anti-MYOC antibody produced in mouse

clone 4F8, purified immunoglobulin, buffered aqueous solution

• 别名: Anti-GLC1A, Anti-GPOA, Anti-JOAG, Anti-JOAG1, Anti-TIGR, Anti-myocilin, Anti-myocilin, trabecular meshwork inducible glucocorticoid response
• UNSPSC代码: 12352203
• NACRES: NA.43

属性

• 生物来源: mouse
• 质量水平: 100
• 偶联物: unconjugated
• 抗体形式: purified immunoglobulin
• 抗体产品类型: primary antibodies
• 克隆: 4F8, monoclonal
• 表单: buffered aqueous solution
• 种属反应性: human
• 技术: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; immunoprecipitation (IP): suitable; indirect ELISA: suitable; western blot: 1-5 μg/mL
• 同位素/亚型: IgG1κ
• GenBank登记号: BC029261
• UniProt登记号: Q99972
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... MYOC(4653)

说明

一般描述

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. (provided by RefSeq)

免疫原

MYOC (AAH29261, 36 a.a. ~ 135 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
QLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQT

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

安全信息

• 储存分类代码: 10 - Combustible liquids
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable
• 个人防护装备: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)