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生物源
mouse
品質等級
共軛
unconjugated
抗體表格
ascites fluid
抗體產品種類
primary antibodies
無性繁殖
TUB-1A2, monoclonal
包含
15 mM sodium azide
物種活性
human, plant, animal
技術
indirect immunofluorescence: 1:800 using cultured chicken fibroblasts
microarray: suitable
western blot: suitable
同型
IgG3
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... TUBA4A(7277) , TUBB(203068)
一般說明
单克隆抗络氨酸微管蛋白（小鼠 IgM 同种型）来源于杂交瘤，该杂交瘤由小鼠骨髓瘤细胞与免疫小鼠脾细胞融合产生。微管蛋白为圆柱形丝状结构，几乎存在于所有真核细胞中。微管蛋白是异二聚体，由 α-微管蛋白和 β-微管蛋白组成。 每种亚基的分子量均为55 kDa，具有相当大的同源性。
微管，是细胞内圆柱状丝状结构，主要由微管蛋白组成，存在于所有真核细胞中。单克隆抗酪氨酸抗体可通过间接免疫荧光标记，对酪氨酸 α 微管蛋白进行免疫细胞化学定位。 单克隆抗酪氨酸抗体与酪氨酸微管蛋白发生特异性反应，适用于牛脑细胞、非洲绿猴肾细胞（Vero），犬肾细胞（MDCK）、袋鼠肾细胞（Potoroo，PtK2）、小鼠垂体瘤细胞（AtT-20）、酵母细胞和非洲爪蟾细胞。
特異性
该抗体在免疫印迹测定中与微管蛋白的C-末端酪氨酸反应，可用于培养细胞或组织切片中该表位的定位。
免疫原
含有 α-微管蛋白羧基端氨基酸的肽
應用
单克隆抗酪氨酸微管蛋白用于：
- 间接免疫荧光标记
- 免疫印迹技术
- 免疫细胞化学染色
生化／生理作用
微管蛋白是微管的主要构建单元。微管蛋白的组装过程涉及微管蛋白酪氨酸化。特异性微管蛋白酪氨酸羧肽酶去除末端酪氨酸，产生末端为谷氨酸残基的 α-微管蛋白；而另一种酶通过在羧基末端添加酪氨酸修饰 α-微管蛋白，从而形成酪氨酸增加和损失的潜在循环。
免責聲明
除非我们的产品目录或产品随附的其他公司文件中另有说明，否则我们的产品仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、体外或体内治疗用途或任何类型的人类或动物消费或应用。
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 1
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商品
Microtubules of the eukaryotic cytoskeleton are composed of a heterodimer of α- and β-tubulin. In addition to α-and β-tubulin, several other tubulins have been identified, bringing the number of distinct tubulin classes to seven.
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