化驗
≥98% (HPLC)
形狀
solid
分子量
(mass spec confirms mol. wt.)
顏色
white
溶解度
DMSO: soluble
儲存溫度
2-8°C
SMILES 字串
N[C@@H](Cc1ccc(O)cc1)C(=O)N2Cc3ccccc3C[C@H]2CN[C@@H](Cc4ccccc4)C(=O)N[C@@H](Cc5ccccc5)C(O)=O
應用
TIPP-Ψ has been used as a positive control during the screening for delta-opioid receptor (DOR) modulators.
生化／生理作用
Selective δ-opioid receptor antagonist.
準備報告
TIPP-Ψ is soluble in DMSO.
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Ting Zhu et al.
Acta pharmacologica Sinica, 29(4), 507-516 (2008-03-25)
To develop a universal high-throughput screening assay based on Galpha15/16- mediated calcium mobilization for the identification of novel modulators of Gprotein- coupled receptors (GPCR). In the present study, CHO-K1 or HEK293 cells were co-transfected with plasmids encoding promiscuous G-protein Galpha15/16
N A Martin et al.
The Journal of pharmacology and experimental therapeutics, 298(1), 240-248 (2001-06-16)
A new class of highly selective delta-opioid receptor antagonists has been recently developed, termed the TIP(P) peptides. Two prototypical compounds in this class are TIPP (H-Tyr-Tic-Phe-Phe-OH) and a derivative, TIPP-psi (H-Tyr-Tic[CH2NH]-Phe-Phe-OH). Surprisingly, both TIPP and TIPP-psi demonstrated inhibition of adenylyl
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