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Merck
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T6443

Sigma-Aldrich

Tyrphostin AG 370

≥98%

别名:

2-Amino-4-(1H-indo-5′-yl)-1,1,3-tricyanobuta-1,3-diene, Tyrphostin B7

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About This Item

经验公式（希尔记法）:
C15H9N5
CAS号:
134036-53-6
分子量:
259.27
MDL编号:
MFCD00236449
UNSPSC代码:
12352200
PubChem化学物质编号:
329826844

方案

≥98%

表单

solid

mp

289 °C

溶解性

DMSO: soluble

储存温度

−20°C

SMILES字符串

NC(\C(=C/c1ccc2[nH]ccc2c1)C#N)=C(\C#N)C#N

InChI

1S/C15H9N5/c16-7-12(15(19)13(8-17)9-18)6-10-1-2-14-11(5-10)3-4-20-14/h1-6,20H,19H2/b12-6-

InChI key

CMMDWEJTQUTCKG-SDQBBNPISA-N

应用

Tyrphostin AG 370 has been used for inhibiting platelet-derived growth factor (PDGF) signaling in human mesenchymal stem cells1,2.

生化/生理作用

Inhibitor of PDGF-induced cell proliferation.

注意

Photosensitive

制备说明

Tyrphostin AG 370 is soluble in DMSO.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
061K1647

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Felicia Ng et al.
Blood, 112(2), 295-307 (2008-03-12)
We compared the transcriptomes of marrow-derived mesenchymal stem cells (MSCs) with differentiated adipocytes, osteocytes, and chondrocytes derived from these MSCs. Using global gene-expression profiling arrays to detect RNA transcripts, we have identified markers that are specific for MSCs and their
Loyal A Goff et al.
Experimental hematology, 36(10), 1354-1369 (2008-07-29)
Human multipotent mesenchymal stromal cells (MSC) have the potential to differentiate into multiple cell types, although little is known about factors that control their fate. Differentiation-specific microRNAs may play a key role in stem cell self-renewal and differentiation. We propose

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