T2315

Anti-Tumor Necrosis Factor Soluble Receptor Type II antibody produced in goat

IgG fraction of antiserum, lyophilized powder

• 别名: CD120b antigen, Etanercept, TNF sRII, TNF-R2, p75 TNF receptor, p75TBPII, p75TNFR, tumor necrosis factor receptor superfamily member 1B
• MDL號碼: MFCD01633483
• 分類程式碼代碼: 51111800
• NACRES: NA.41

属性

• 生物源: goat
• 品質等級: 200
• 共軛: unconjugated
• 抗體表格: IgG fraction of antiserum
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: lyophilized powder
• 物種活性: human
• 技術: immunocytochemistry: 5-15 μg/mL (detects TNF RII in human PBLs); western blot: 1 μg/mL (detects rhs TNF RII at 5 ng/lane under non-reducing conditions)
• UniProt登錄號: P20333
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... TNFRSF1B(7133)

说明

一般說明

TNF RII is a type I transmembrane glycoprotein primarily expressed on hematopoietic cells and is designated TNFRSF1B. TNF RII is a highaffinity receptor for TNF alpha and TNF beta. A soluble form of the receptor generated by proteolytic cleavage functions as a TNF antagonist.

特異性

The antibody detects human TNF sRII and shows no cross-reactivity with recombinant human TNF sRI.

免疫原

recombinant human TNF soluble receptor II (TNF sRII) expressed in Escherichia coli. The immunogen is the non-glycosylated, N-terminal methionyl form of the naturally-occurring human soluble type II receptor for TNF, minus 53 amino acids from the proline-rich region just exterior to the transmembrane domain.

應用

Western Blot: 1 ug/mL detects rhs TNF RII at 5 ng/lane under non-reducing conditions
Immunocytochemistry: Concentration of 5-15 ug/ml detects TNF RII in human peripheral blood lymphocytes

Optimal dilutions should be determined by the end user.

外觀

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline (pH 7.4) and 5% trehalose.

其他說明

Protein A or G purified

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable