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Merck
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主要文件

SRP6099

Sigma-Aldrich

GSTM1 from mouse

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

别名:

GST 1-1, GST class-mu1, Glutathione S-transferase Mu 1, pmGT10

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About This Item

UNSPSC代码:
12352200
NACRES:
NA.32

生物来源

mouse

重组

expressed in E. coli

方案

≥95% (SDS-PAGE)

表单

liquid

分子量

25.9 kDa

包装

pkg of 100 μg

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

mouse ... GSTM1(14862)

一般描述

GSTM1 (glutathione S-transferase μ 1) belongs to the superfamily of glutathione-S-transferases. It belongs to the μ class of soluble GSTs. GSTM1 is strongly expressed in the kidneys.

生化/生理作用

Members of GST (glutathione S-transferase) superfamily are responsible for the metabolism of various reactive oxygen species and xenobiotics. GSTM1 (GST μ 1) plays a significant role in vascular homeostasis. Humans with null allele, GSTM1(0), are at increased risks for colon and lung cancers, hypertension, and atherosclerosis, and have higher DNA changes in atherosclerotic lesions of the abdominal aorta.

外形

1 mg/mL solution in PBS (pH 7.4) containing 5 mM Glutathione

制备说明

Centrifuge the vial prior to opening.

其他说明

MPMILGYWNV RGLTHPIRML LEYTDSSYDE KRYTMGDAPD FDRSQWLNEK FKLGLDFPNL PYLIDGSHKI TQSNAILRYL ARKHHLDGET EEERIRADIV ENQVMDTRMQ LIMLCYNPDF EKQKPEFLKT IPEKMKLYSE FLGKRPWFAG DKVTYVDFLA YDILDQYRMF EPKCLDAFPN LRDFLARFEG LKKISAYMKS SRYIATPIFS KMAHWSNK

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Glutathione S-transferase-micro1 regulates vascular smooth muscle cell proliferation, migration, and oxidative stress.
Yang Y, et al.
Hypertension, 54, 1360-1360 (2009)

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