生物来源
mouse
重组
expressed in CHO cells
方案
90-95% (SDS-PAGE)
表单
lyophilized
分子量
50.0 kDa
包装
pkg of 10 μg
杂质
Endotoxin, tested
NCBI登记号
运输
wet ice
储存温度
−20°C
基因信息
mouse ... CD14(12475)
一般描述
CD14 acts as a receptor for endotoxin (LPS), is expressed strongly on monocy¬tes, macrophages and weekly at surface of neutrophiles. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor LPS-LBP (lipopolysaccharide binding protein)-complexes. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids, acts at physiological concentrations as LPS agonist and has at higher concentrations an antagonizing effect in cell activation. The myeloid differentiation antigen CD14 acts as the major receptor for bacterial LPS. The dominant form of the recombinant wild type CD14 is the 50 kDa protein. This is a His-tagged protein.
外形
Lyophilized from a concentrated protein solution (1 mg/ml) containing PBS, pH 7.2
重悬
Centrifuge the vial prior to opening. Reconstitute in 10 μl of ultra-pure distilled water. This solution can then be diluted into other aqueous buffers.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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