SRP5328

NEK5, active, GST tagged human

PRECISIO^®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• 别名: MGC75495
• CAS号: 2249882-56-0
• UNSPSC代码: 12352200
• NACRES: NA.32

属性

• 生物来源: human
• 重组: expressed in baculovirus infected Sf9 cells
• 产品线: PRECISIO^®
• 方案: ≥70% (SDS-PAGE)
• 表单: buffered aqueous glycerol solution
• 比活: 80-120 nmol/min·mg
• 分子量: ~84 kDa
• NCBI登记号: NM_199289
• 应用: cell analysis
• 运输: dry ice
• 储存温度: −70°C
• 基因信息: human ... NEK5(341676)

说明

一般描述

NEK5 or NIMA (never in mitosis gene a)-related kinase 5 is a serine/threonine kinase that is involved in cell cycle regulation. NEK5 has been shown to interact with NEK6 and NEK5 are required for the ibo1/nek6 ectopic outgrowth phenotype in epidermal cells. NEK6 interacts and co-localizes with NEK5 in a transient expression assay. The ibo1-3 mutation markedly increases the interaction between NEK6 and NEK5. NEK6 forms heterodimers with NEK5 to regulate cortical microtubule organization possibly through the phosphorylation of β-tubulins. The NEK5 gene is conserved in chimpanzee, cow, mouse, rat, and chicken.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

制备说明

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

法律信息

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable