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Merck

SRP5265

Sigma-Aldrich

HDAC1, active, GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

别名:

DKFZp686H12203, GON-10, HD1, RPD3, RPD3L1

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.32

重組細胞

expressed in baculovirus infected Sf9 cells

化驗

≥70% (SDS-PAGE)

形狀

buffered aqueous glycerol solution

比活性

7565-11765 RLU/min·ng

分子量

~88 kDa

NCBI登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... HDAC1(3065)

一般說明

HDAC1 or Histone deacetylase 1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex which plays a key role in the regulation of eukaryotic gene expression. HDAC1 interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis. HDAC1 is an essential element of the co-activation system for IFN-induced gene regulation and antiviral responses.

外觀

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

準備報告

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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